| 舌下脱敏治疗儿童过敏性支气管哮喘疗效观察 |
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| 引用本文： | 常青. 舌下脱敏治疗儿童过敏性支气管哮喘疗效观察[J]. 儿科药学杂志, 2011, 17(6): 27-29 |
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| 作者姓名： | 常青 |
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| 作者单位： | 江苏省无锡市第八人民医院映山河儿童医院,江苏无锡,214002 |
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| 摘 要： | 目的:探讨舌下特异性免疫治疗(SLIT)对于儿童过敏性支气管哮喘的疗效.方法:将72例儿童过敏性支气管哮喘患儿随机分成两组各36例,治疗组在吸入低剂量糖皮质激素(相当于200 μg布地奈德等效剂量)的基础上加用舌下含服粉尘螨滴剂治疗,对照组单纯吸入低剂量糖皮质激素,疗程均为18个月.观察两组在治疗期间人均累计哮喘急性发...
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| 关 键 词： | 支气管哮喘 特异性免疫治疗 粉尘螨滴剂 |
The Impacts of Sublingual Desensitization Treatment with Dermatophagoides Farinae Drops on Allergic Bronchial Asthma of Children |
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| Chang Qing. The Impacts of Sublingual Desensitization Treatment with Dermatophagoides Farinae Drops on Allergic Bronchial Asthma of Children[J]. Journal of Pediatric Pharmacy, 2011, 17(6): 27-29 |
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| Authors: | Chang Qing |
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| Affiliation: | Chang Qing (Wuxi No.8 People’s Hospital,Yingshanhe Children’s Hospital,Jiangsu Province,Jiangsu Wuxi 214002,China) |
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| Abstract: | Objective: To investigate the effects of sublingual immunotherapy(SLIT) on treating allergic bronchial asthma of children.Methods: Randomly assigned 72 subjects with allergic bronchial asthma into two groups,both groups received treatment with a low-level of glucocorticoid(equal to 200 μg budesonide).The treatment group(36 cases) received an additional treatment with dermatophagoides farinae drops.The treatment lasted 18 months.Results: T-test results suggested that the treatment group had significantly better results on average allergic responses per person(P<0.01),lasting days for each allergic response(P<0.01),night symptom scores(P<0.05),total IgE level(P<0.01),forced expiratory volume in 1 s(FEV1)(P<0.01),peak expiratory flow(PEF)(P<0.05),as compared to the control group.Conclusions: Sublingual immunotherapy(SLIT) with dermatophagoides farinae drops can significantly increase the effectiveness when treating allergic bronchial asthma of children. |
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| Keywords: | Allergic bronchial asthma Sublingual immunotherapy Dermatophagoides farinae drops |
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