Abstract: | Calcinated aortic stenosis developing in the elderly is erroneously referred to atherosclerotic lesion of the valve or is thought to be rheumatic heart defect undetected previously. The atherosclerotic hypothesis is rejected by foreign investigated while a conception of postrheumatic damage is discussed in the light of immune inflammation found in the calcinated valve. Immunogenetic testing was used for investigation of correlations between senile aortic stenosis and rheumatic fever. |