蔬菜与云锡矿工肺癌的队列研究

目的 为了解蔬菜与云锡（ＹＴＣ）矿工肺癌危险性的关系。方法 研究食物频率问卷（ＦＦＱ）资料中蔬菜摄入频率的重复性和有效性，在此基础上用ｘ＾２检验、单因素、多因素ｃｏｘ回归分析了云锡矿工肺癌高危人群不同蔬菜摄入频率、总蔬菜摄入量与其发生肺癌相对危险性的关系。结果 冬瓜、黄瓜、菠菜、鲜辣椒、鲜黄豆、红薯、芦笋、嫩竹笋、青玉米等１１种蔬菜摄入频率的重复性和有效性较好（ｒ＝０．２０～０．３３，ｐ〈０．０５

A cohort study on the relationship between vegetable intake and risks of lung cancer in the Tin Corporation(YTC)miners in Yunnan

OBJECTIVE: To understand the relationship between vegetable intake and risk of lung cancer in the Tin Corporation (YTC) miners in Yunnan. METHODS: The reproducibility and validity of frequency of vegetable intake in Food Frequency Questionnaire (FFQ) were studied and the correlations between different vegetable intake and frequency and lung cancer relative risk among high risk population of lung cancer by Chi-square, single- and multi-Cox regression were analyzed. RESULTS: Results showed that the reproducibility and validity of wax gourd, cucumber, spinach, wild celery, fresh bush pepper, fresh soybean, sweet potatoes, asparagus, fresh bamboo shoot were good (r = 0.20 - 0.33, P < 0.05); There were significantly different incidences of lung cancer in different frequencies of wax gourd, cucumber, wild celery, fresh bush pepper out of 11 vegetables intake, and also in different total vegetable intakes (chi(2) = 8.83 - 30.64, P < 0.05). 11 vegetables and total vegetable intake were significantly negatively correlated with risks of lung cancer (RR < 1, P < 0.05). Only 2 vegetable frequencies were negatively correlated with risk of lung cancer by adjusting confounders such as age, occupational history, and smoking (P < 0.05). CONCLUSION: This suggested that vegetables intake may have a role in decreasing the incidence of lung cancer.