膜诱导组织再生技术用于牙种植的实验研究I．扩大牙种植适应证

目的为临床应用膜诱导组织再生技术扩大牙种植适应证提供理论依据。方法在拔除狗前磨牙的同时，造成颊侧骨板缺损，即刻种植羟基磷灰石涂层钛种植体或纯钛种植体，并运用胶原膜覆盖颊侧种植体暴露面和骨面，观察种植体周骨组织再生情况。结果经过一年的放射学和组织学观察，表明种植体周骨组织有不同程度的再生，大多数种植体稳固。结论膜诱导组织再生技术可作用于牙种植的临床治疗。

Experimental StudyofMembrane Guied TissueRegeneration Sround Dental Implants I.Expanding the Indication ofDental Inplants

The purpose of this study is providing theoretic evidence for applying guied tissue regeneration to dental unplant so as to expand the indication. Methods: Mandibular premolar 1, 2 and 3 of six adult dogs were extracte bilaterally, and buccal bone plate defects were created and measured. Eighteen screw- shaped pure titanum implants and cylindric hydroxyapatite - coated titanum implants were placed into the fresh extraction sockets. Eighteen implants were as controls, implants on the experimantal laterals were caued with collagen membranes. After 3 months, 6 months, and 12 months, the dogs were sacrificed and all specimens retrived for radiographic and histologic evaluation.Result: this study indicated that collagen membrane improve bone regeneration around dental implant. Conclnsion: Membrane guided tissue regeneration could be used in clinical treatment of dental implant.