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The Genetics of Complex Cholestatic Disorders |
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| Authors: | Gideon M. Hirschfield Roger W. Chapman Tom H. Karlsen Frank Lammert Konstantinos N. Lazaridis Andrew L. Mason |
| Affiliation: | 1 Centre for Liver Research, National Institute for Health Research Biomedical Research Unit, University of Birmingham, Birmingham, England;2 Department of Gastroenterology, John Radcliffe Hospital, Oxford, England;3 Research Institute for Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway;4 Department of Medicine II, Saarland University Medical Center, Homburg, Germany;5 Center for Basic Research in Digestive Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota;6 Centre of Excellence in Gastrointestinal Inflammation and Immunity Research, University of Alberta, Edmonton, Alberta, Canada |
| Abstract: | |
| Keywords: | AH, ancestral haplotype AMA, antimitochondrial antibodies GGT, γ-glutamyltransferase GWAS, genome-wide association studies IBD, inflammatory bowel disease IL, interleukin LPAC, low phospholipid-associated cholelithiasis MHC, major histocompatibility complex PBC, primary biliary cirrhosis PDC-E2, pyruvate dehydrogenase complex E2 PFIC, progressive familial intrahepatic cholestasis PSC, primary sclerosing cholangitis Th, T-helper TNF, tumor necrosis factor |
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