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Identification of Molecular Subtypes of Gastric Cancer With Different Responses to PI3-Kinase Inhibitors and 5-Fluorouracil
Authors:Zhengdeng Lei  Iain Beehuat Tan  Kakoli Das  Niantao Deng  Hermioni Zouridis  Sharon Pattison  Clarinda Chua  Zhu Feng  Yeoh Khay Guan  Chia Huey Ooi  Tatiana Ivanova  Shenli Zhang  Minghui Lee  Jeanie Wu  Anna Ngo  Sravanthy Manesh  Elisabeth Tan  Bin Tean Teh  Jimmy Bok Yan So  Liang Kee Goh  Alex Boussioutas  Tony Kiat Hon Lim  Horst Flotow  Patrick Tan  Steven G. Rozen
Affiliation:1 Centre for Computational Biology, Duke-National University of Singapore Graduate Medical School, Singapore;2 Cancer and Stem Cell Biology Program, Duke-National University of Singapore Graduate Medical School, Singapore;3 National University of Singapore Graduate School for Integrative Sciences and Engineering, Singapore;4 Department of Medical Oncology, National Cancer Centre Singapore, Singapore;5 Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, University of Melbourne, Victoria, Australia;6 Department of Medicine, National University Health System, Singapore;7 Department of Gastroenterology and Hepatology, National University Health System, Singapore;8 Cellular and Molecular Research, National Cancer Centre Singapore, Singapore;9 The Experimental Therapeutics Centre, Agency for Science, Technology and Research, Singapore;17 Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore;10 National Cancer Centre Singapore - Van Andel Research Institute Translational Research Laboratory, National Cancer Centre Singapore, Singapore;11 Department of Surgery, National University Health System, Singapore;12 Department of Medicine, Royal Melbourne Hospital, Victoria, Australia;13 Department of Gastroenterology, Royal Melbourne Hospital, Victoria, Australia;14 Department of Gastroenterology, Western Hospital, Victoria, Australia;15 Department of Pathology, Singapore General Hospital, Singapore;16 Cancer Science Institute of Singapore, National University of Singapore, Singapore
Abstract:
Keywords:Stomach Cancer   GC-Class   Personalized Cancer Treatment   Cancer Classification   PI3K
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