喹硫平与利培酮治疗精神分裂症的效果分析

目的 探讨喹硫平与利培酮治疗精神分裂症的效果.方法 选择82例患有精神分裂症的患者,随机分为对照组和治疗组,每组各41例,对照组患者给予利培酮治疗,治疗组患者给予喹硫平治疗.结果 治疗组患者的总有效率为90.2％,显著优于对照组的68.3％,差异有统计学意义（P＜0.05）；治疗组的精神分裂症状控制时间及接受治疗平均时间均明显少于对照组,差异有统计学意义（P＜0.05）；治疗组的不良反应发生率显著低于对照组,差异有统计学意义（P＜0.05）.结论 喹硫平治疗精神分裂症的效果良好,不良反应发生率低,值得临床推广应用.

Effect analysis of quetiapine and risperidone in the treatment of schizophrenia

Objective To discuss the effect of quetiapine and risperidone in the treatment of schizophrenia. Methods 82 patients with schizophrenia were selected and randomly divided into treatment group and control group with 41 pa- tients in each group.Patients in the control group were given risperidone while patients in the treatment group were given quetiapine. Results The total effective rate in the treatment group was 90.2% while it showed 68.3% in the con- trol group,there was statistically difference existed （P〈0.05）.Schizophrenia control time and the total treatment time in the treatment group was significantly shorter than that of the control group （P〈0.05）.The adverse reactions of treatment group was significantly lower than that of control group,the differences are statistically significant（P〈0.05）. Conclusion Quetiapine has a sound clinical effect in the treatment of patients with schizophrenia.