| 高效液相色谱法测定妇康宁片中阿魏酸的含量 |
| |
| 引用本文： | 陈阿丽,杨永霞,梁生旺,王淑美. 高效液相色谱法测定妇康宁片中阿魏酸的含量[J]. 中国当代医药, 2013, 0(28): 71-72,75 |
| |
| 作者姓名： | 陈阿丽 杨永霞 梁生旺 王淑美 |
| |
| 作者单位： | 广东药学院,广州510006 |
| |
| 基金项目： | 国家自然科学基金（81073024） |
| |
| 摘 要： | 目的建立高效液相色谱法测定妇康宁片中阿魏酸含量的方法。方法色谱柱为SinoChrom ODS-BPC18柱（4．6mm×250mm，5μm）；流动相为乙腈-0．1％磷酸（22：78）；流速：1．0ml/min；检测波长：316nm；柱温：25℃。结果阿魏酸在0．0014～0．0280mg／ml范围内呈良好的线性关系（r=0．9998），平均回收率为99．2％，RSD=1．0％（n=6）。结论本方法操作简单、快速。可用于测定妇康宁片中阿魏酸的含量。
|
| 关 键 词： | 高效液相色谱 妇康宁片 阿魏酸 含量测定 |
The content determination of ferulic acid in Fukangning tablets by HPLC |
| |
| CHEN A-li,YANG Yong-xia,LIANG Sheng-wang,WANG Shu-mei. The content determination of ferulic acid in Fukangning tablets by HPLC[J]. http://www.botanicus.org/, 2013, 0(28): 71-72,75 |
| |
| Authors: | CHEN A-li YANG Yong-xia LIANG Sheng-wang WANG Shu-mei |
| |
| Affiliation: | Guangdong Pharmaceutical University,Guangzhou 510006,China |
| |
| Abstract: | Objective To establish a method for the content determination of ferulic acid in Fukangning tablets by HPLC. Methods SinoChrom ODS-BP C18 column （4.6 mm×250 mm,5 μm） was used;the mobile phase consisted of acetonitrile-0.1% phosphate acid （22：78） and the flow rate was 1.0 ml/min.The detection wavelength was 316 nm and the column temperature was at 25℃. Results Ferulic acid showed a good linear relationship （r=0.9998） in the range of 0.0014-0.0280 mg/ml with the addition recovery rate of 99.2% and RSD of 1.0%（n=6）. Conclusion The method is simple and accurate with good repetition and high precision,which was suitable for the determination of ferulic acid in Fukangning tablets. |
| |
| Keywords: | High performance liquid chromatography Fukangning.tablet Ferulic acid Content determination |
| 本文献已被 维普 等数据库收录！ |
|
