乳腺癌前哨淋巴结解剖学定位及其临床观察

目的探究乳腺癌前哨淋巴结（SLN）的解剖学定位及其在乳腺癌腋淋巴结清除中的意义。方法选取T1-3N0M0分期乳腺癌患者共80例，实施核素法、染料法检测SLN，以99mTC标记的硫胶体作为标志物，注射亚甲蓝，SLN活检之后选择性实施腋淋巴结清除术。结果检测出SLN共79例，核素法及染料法检验成功率均为97．50％（78／80），两种方法联合检测成功率为98．75％（79／80）。核素标示与染料标示SLN检测结果完全相同。结论核素法、染料法检测SLN效果相近，联合两种定位方式可为乳腺癌诊断及治疗提供可靠的临床指导。

Anatomical location and clinical observation of sentinel lymph node of breast cancer

Objective To investigate the anatomical location of sentinel lymph nodes （SLN） of breast cancer and its significance in axillary lymph node disescetion. Methods 80 patients with breast cancer of T1-3N0M0 stage were selected and detected for SLN by implementation of nuclide method and dye method, using sulfur colloid labeled by 99mTC as markers and injection of methylene blue. Selective axillary lymph node disescetion was implemented after biopsy of SLNB. Results SLN were detected in total of 79 cases with successful detection rate of both nuclide method and dye method of all 97.50% （78/80） and successful joint detection rate of both methods of 98.75% （79/80）. The detection resuits of SLN labeled by nuclide and dye was identical. Conclusion The detection effects of SLN labeled by nuclide and dye is similar; joint detection of both methods can provide reliable clinical direction for diagnosis and treatment of breast cancer.