特比萘酚联合氟康唑治疗真菌性角膜炎的效果分析

目的研究特比萘酚联合氟康唑治疗真菌性角膜炎的效果。方法选取本院2009年6月～2011年2月收治的52例真菌性角膜炎患者，随机分为对照组与治疗组，每组各26例。对照组使用氟康唑进行治疗，治疗组使用氟康唑联合特比萘酚进行治疗。结果治疗组的有效率为92．3％，明显高丁对照组的80．8％，治疗组的治愈天数为（36．19±13．18）d明显短于治疗组的（23．75±12．92）d；两组的不良反应比较，后异有统计学意义（P〈0.01）。结论特比萘酚联合氟康唑治疗真菌性角膜炎的治疗效果较好，值得临床推广应用。

Effect analysis of terbinafine combined with fluconazole treating fungal keratitis

Objective To study the effect of terbinafine combined with fluconazole treating fungal keratitis. Methods 52 cases with fungal keratitis were randomly divided into the control group （n=26） and the treatment group （n=26） from June 2009 to February 2011 in our hospital, the control group was treated with fluconazole,the treatment group was treated with fluconazole combined with terbinafine. Results The effective rate （92.3%） in the treatment group was sig nificantly than that （80.8%） in the control group;the cure time[（23.75±12.92）d ] in the treatment group was significantly shorter than that[（36.19±13.18）d] in the control group （P〈0.05）;adverse reactions of the two groups was compared,there was a statistical difference （P〈0.01）. Conclusion The effect of terbinafine combined with fluconazole treating fungal keratitis is better,and it is worthy of clinical promotion and application.