我院530例药品不良反应报告分析

目的：分析我院2006～2008年上报的药物不良反应（ADR）发生规律和特点。方法：对上报的530例药品不良反应分别从患者年龄、给药途径、药品种类、ADR临床表现等方面进行回顾性分析与评价。结果：530例ADR报告中共涉及13大类药物，药品种类共184种，其中抗感染药物引起的ADR最多，占34．15％；给药途径中静脉用药引起的ADR399例，占75．28％；ADR临床表现主要为皮肤及其附件损害，占31．70％。结论：必须重视药品不良反应监测工作，加强药师与临床的沟通交流，减少或避免ADR的发生。

Analysis of 530 ADR Case Reports in Our Hospital

Objective： To investigate and analyze the regular pattern and characteristics of adverse drug reactions （ADRs） in our hospital from 2006 to 2008. Method： Five hundreds and thirty ADR cases reported in our hospital were analyzed retrospectively in respect of age of patients, route of administration, drug kinds, systems and organs of ADR involved etc. Result： A total of 184 kinds of drugs belong to 13 major categories of drugs were involved in 530 ADR events,antibacterial drugs dominated the first place（34.15% ）. Three hundreds and ninety nine ADRs （75.28%） were induced by intravenous route. The major systems involved were skin and its appendages （31.70% ）. Conclusion： It is important to intensify ADR monitoring, facilitating communication between pharmacists and clinician in order to reduce or avoid ADR events.