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双氯芬酸乳胶剂颈部涂抹辅助治疗急性咽部炎症
引用本文:张浩,陈学明,王士礼,何士方,肖宽林,金伟. 双氯芬酸乳胶剂颈部涂抹辅助治疗急性咽部炎症[J]. 中国新药与临床杂志, 2001, 20(6): 484-486
作者姓名:张浩  陈学明  王士礼  何士方  肖宽林  金伟
作者单位:上海第二医科大学附属瑞金医院
摘    要:目的 :探讨双氯芬酸乳胶剂颈前涂抹对急性咽部炎症的疗效和安全性。方法 :急性咽部炎症病人 3 0例在常规治疗基础上 ,加用双氯芬酸乳胶剂颈前皮肤局部涂抹 ,4g ,qid ,连用 3d ;另设对照组2 0例作常规治疗 ,仅用抗生素及中药口服。结果 :双氯芬酸组治疗后咽痛和吞咽疼痛分值下降 (P <0 .0 1) ,对照组在治疗后 72h疼痛分值才有明显下降。治疗后 2 4h双氯芬酸组对疾病总有效率为 60% ,高于对照组 (2 0 % ,P <0 .0 5 )。 2组病人均未发现不良反应。结论 :双氯芬酸乳胶剂局部涂抹治疗急性咽部炎症 ,止痛有效 ,使用安全。

关 键 词:双氯芬酸  咽炎  疼痛
文章编号:1007-7669(2001)06-0484-03

Topical application of diclofenac emulgel in treating acute pharyngeal inflammation
ZHANG Hao,CHEN Xue Ming,WANG Shi Li,HE Shi Fang,XIAO Kuan Lin,JIN Wei. Topical application of diclofenac emulgel in treating acute pharyngeal inflammation[J]. Chinese Journal of New Drugs and Clinical Remedies, 2001, 20(6): 484-486
Authors:ZHANG Hao  CHEN Xue Ming  WANG Shi Li  HE Shi Fang  XIAO Kuan Lin  JIN Wei
Abstract:AIM: To observe the efficacy and safety of diclofenac emulgel in treating acute pharyngeal inflammation. METHODS: Thirty patients (M 19, F 11; age 36 a± s 8 a) with acute pharygeal inflammation were treated with diclofenac emulgel topically, 4g, qid for 3 d, in addition to conventional therapy (anti infection therapy etc). Other 20 patients served as control (M 12, F 8; age 35 a±7 a) were treated with conventional therapy only. RESULTS: The total efficiency rate of diclofenac group was 60% vs that of the control group 20% on d 1 ( P <0.05). However a comparison of the evaluated parameters did not reveal any statistical significance at the end of the study. No serious systemic or local adverse reactions were found in 2 groups. CONCLUSION: The topical use of diclofenac emulgel in treating acute pharyngeal inflammation is satisfactory.
Keywords:diclofenac  pharyngitis  pain
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