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Weight-based vs body surface area-based fluid resuscitation predictions in pediatric burn patients
Affiliation:1. Department of Surgery, Division of Pediatric Surgery, Wayne State University/Children''s Hospital of Michigan, 3901 Beaubien Blvd. #2129, Detroit, MI 48201, USA;2. Department of Surgery, Division of Pediatric Surgery, Wayne State University/Children''s Hospital of Michigan, 3901 Beaubien Blvd. #2215, Detroit, MI 48201, USA;3. Department of Surgery, Division of Pediatric Surgery, Wayne State University/Children''s Hospital of Michigan, 3901 Beaubien Blvd. #2120, Detroit, MI 48201, USA;4. Department of Surgery, Division of Pediatric Surgery, Wayne State University/Children''s Hospital of Michigan, 3901 Beaubien Blvd. #2121, Detroit, MI 48201, USA;1. Oyumino Central Hospital, 6-49-9 Oyumino-Minami, Midori-ku, Chiba 266-0033, Japan,;2. Department of Plastic, Reconstructive, and Aesthetic Surgery, Chiba University Hospital, 1-8-1 Inohana, Chuo-ku, Chiba 260-8677, Japan;3. Hatano Research Institute, Food and Drug Safety Center, 729-5 Ochiai, Hatano, Kanagawa 257-8523, Japan,;4. Department of Chemistry, Nara Medical University, 840 Shijo-cho, Kashihara, Nara 634-8521, Japan;5. Department of Plastic, Reconstructive Syrgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan;1. Department of Plastic, Reconstructive and Aesthetic Surgery, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey;2. Department of Plastic, Reconstructive and Aesthetic Surgery, Sirnak State Hospital, Sirnak, Turkey;3. Department of Clinical Pathology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey;4. Department of Anesthesiology and Reanimation, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey;1. Resuscitation Research Laboratory, Dept. of Anesthesiology, University of Texas Medical Branch, Galveston, TX, United States;2. Canniesburn Plastic Surgery Unit, Glasgow Royal Infirmary, 84 Castle Street, Glasgow, G4 0SF, UK;1. Department of Surgery, Wayne State University School of Medicine, Detroit, MI;2. Children?s Hospital of Michigan, 3901 Beaubien St, Detroit, MI 48201
Abstract:Treatment for pediatric burns includes fluid resuscitation with formulas estimating fluid requirements based on weight and/or body surface area (BSA) with percent total body surface area burn (%TBSA burn). This study evaluates the risk of complications using weight-based resuscitation in children following burn injuries and compares fluid estimates with those that incorporate BSA. A retrospective review was conducted on 110 children admitted to an ABA-verified urban pediatric burn center over 12 years. Patients had ≥ 15% TBSA burn and were resuscitated with the weight-based Parkland formula. BSA-based Galveston and BSA-incorporated Cincinnati formula predictions were calculated. Complications were collected throughout hospital stay. Patients were classified into weight groups based on percentile. This study included 11 underweight, 60 normal weight, 18 overweight, and 21 obese children. Total fluid administered was higher as percentile increased; however, overweight children received more fluid than the obese (p = 0.023). The Galveston formula underpredicted fluid given over the first 24 h post-injury (p = 0.042); the Parkland and Cincinnati formula predictions did not significantly differ from fluids given. Further research is needed to determine the value of weight-based vs BSA-based or incorporated formulas in reducing risk of complications.
Keywords:Pediatric  Obesity  Fluid resuscitation  Parkland formula
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