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The Jarisch-Herxheimer reaction in leptospirosis.
Authors:C. Vaughan   C. C. Cronin   E. K. Walsh     M. Whelton
Affiliation:Cork Regional Hospital, Department of Medicine, Wilton, Ireland.
Abstract:Three patients with leptospirosis whose condition worsened after initiation of antibiotic therapy are reported. Their clinical deterioration appeared to be due to the development of the Jarisch-Herxheimer reaction rather than to progression of their underlying infection. Relevant aspects of the management of patients with leptospirosis are discussed.
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