| Abstract: | Histochemical, morphological and ultrastructural studies of 208 cases of carcinoma of various organs (stomach, colon, lung, mammary gland, bladder, thyroid) and 159 cases of precancerous or risk disease of these organs are given. The degree and properties of local immune reactions in precancer, incipient and advanced carcinoma are compared. The degree of the epithelium and stroma infiltration with the immunocompetent cells as well as the cell composition of the infiltrate vary at different stages of tumour development and depending on its histological structure. Cytotoxic effect of the immunocompetent cells on the tumour cells is revealed, this effect decreasing in advanced carcinoma. |
