上海市松江区大气污染与脑卒中急性期死亡的关联性分析

[目的]探究大气污染与脑卒中急性期死亡的关联性,以及大气污染环境中脑卒中急性期死亡的易感人群情况.[方法]汇总上海市松江区2012—2014年大气污染数据,并收集户籍人口脑卒中急性期死亡的全部病例,采用时间分层-病例交叉设计方法分析两者间关系,并确立易感人群.[结果]共纳入了514例脑卒中急性期死亡病例.研究期间内,P...

Association between ambient air pollution and fatal stroke mortality in Songjiang District of Shanghai

[Objective]To investigate the risk of fatal stroke mortality associated with short-term exposure to air pollution,and to determine the susceptible population.[Methods]In this study,daily stroke mortalities of adults between 2012 and 2014 in Songjiang District,Shanghai were collected.Time-stratified case-crossover approach was used to assess the association between daily concentrations of air pollutants and fatal stroke mortalities.[Results]This study included 514 patients who died from acute strokes.The average concentrations during the study period were 77.45μg·m^-3for PM_2.5,21.22μg·m^-3for SO₂,and 57.59μg·m^-3for NO₂.The fatal stroke mortality of adults under the age of 65 was found to be significantly associated with NO₂.At the time of a Lag of 2 d and 03 d,a significantly higher risk of fatal stroke mortality in relation to NO₂exposure was observed,and the OR values of ischemic stroke mortality for people were 3.86(1.53-9.75)and 5.83(1.40-24.34)respectively.People over the age of 65 were more sensitive to increased PM_2.5concentrations,at the time of a Lag of 03 d,fatal strokes increased by 28%when PM_2.5levels increased.A significantly higher risk of fatal stroke mortality in relation to increase of NO₂concentration was observed among people who were overweight or obese.[Conclusion]A significantly higher risk of fatal stroke mortality is associated with the increase of PM_2.5and NO₂.The results also suggest that the susceptible population should take additional precautions to avoid or reduce the risk of fatal strokes.