十二指肠副乳头插管置入胰管支架的安全性评价

目的 评价经十二指肠副乳头插管置入胰管支架的安全性。方法 回顾性分析2016年1月至2021年8月于首都医科大学附属北京友谊医院行十二指肠乳头插管置入胰管支架治疗胰腺疾病的114例患者的临床资料。其中经主乳头插管88例,经副乳头插管26例。比较两组患者年龄、性别、既往病史、内镜逆行胰胆管造影术(endoscopic retrograde cholangiopancreatography,ERCP)手术史、术者、术前凝血功能、经胰管括约肌切开术、困难插管、置入胰管支架个数、术后并发症发生率、术后住院时间的差异,并采用二分类Logistic回归法分析术后并发症的独立危险因素。结果 两组患者术后并发症发生率和术后住院时间的差异无统计学意义(P>0.05),二分类Logistic回归法显示,副乳头插管与术后并发症的无关联(P>0.05)。结论 根据目前有限的数据,经十二指肠副乳头插管置入胰管支架与经主乳头插管相比,不会增加术后并发症的发生率和术后住院时长。

Safety evaluation of pancreatic duct stent placement through duodenal accessory papilla cannulation

Objective To evaluate the safety of pancreatic duct stent placement through duodenal accessory papilla cannulation. Methods Data of 114 patients with pancreatic diseases who underwent duodenal papilla cannulation and pancreatic stent placement in Beijing Friendship Hospital from January 2016 to August 2021 were analyzed retrospectively. There were 88 patients underwent the main papilla cannulation,while 26 patients treated by accessory papilla cannulation.We compare the differences of the age, sex, previous history, history of endoscopic retrograde cholangiopancreatography (ERCP) operation, operator, preoperative blood coagulation function, endoscopic pancreatic sphincterotomy, difficult cannulation, number of pancreatic duct stents, post-ERCP complications, the length of hospital stay after ERCP between two groups.The independent risk factors for postoperative complications were analyzed by binary Logistic regression.Results There was no significant difference in the incidence of postoperative complications and length of hospital stay after ERCP between the two groups (P>0.05), and binary Logistic regression showed that duodenal accessory papilla cannulation was not a risk factor for post-ERCP complications(P>0.05). Conclusion According to the current limited data, the placement of pancreatic duct stent through duodenal accessory papilla cannulation will not increase the incidence of the incidence of post-ERCP complications and the length of hospital stay compared with main papilla cannulation.