急诊重症患者机械通气脱机后发生创伤后应激障碍的危险因素分析

目的:分析急诊重症患者于机械通气脱机后发生创伤后应激障碍(PTSD)的危险因素.方法:回顾性选择某院急诊室收治的160例重症患者为研究对象,统计患者机械通气脱机后PTSD的发生率,并以患者发生PTSD为因变量,以可能造成PTSD的相关因素(患者基线资料)为自变量,分析PTSD发生的危险因素.结果:160例患者机械通气脱...

Analysis of the Risk Factors of Post-traumatic Stress Disorder (PTSD) after Mechanical Ventilation in Critical Emergency Patients

Objective:To analyze the risk factors of post-traumatic stress disorder(PTSD)in critical emergency patients after mechanical ventilation.Methods:160 cases of severe patients in emergency department of a hospital were retrospectively selected as the subjects.The incidence of PTSD after mechanical ventilation was analyzed,and taking the occurrence of PTSD as the dependent variable and the related factors that may cause PTSD(patient baseline data)as the independent variable,the risk factors of PTSD were analyzed.Results:50 patients developed PTSD after mechanical ventilation in 160 patients,the incidence of PTSD was 31.25%(50/160).160 patients were divided into PTSD group(n=50)and non-PTSD group(n=100),the proportion of PTSD combined with underlying diseases,mechanical ventilation time>7 days,the proportion of poor sedation effect in PTSD group were higher than that of non-PTSD group(P<0.05).The APACHE-Ⅱscore in PTSD group was higher than that in non-PTSD group(P<0.05),and the levels of Cor,5-HT and INF-γin PTSD group were higher than those in non-PTSD group(P<0.05).Conclusion:The important risk factors for PTSD after mechanical ventilation in critical emergency patients were complicated with underlying diseases,mechanical ventilation time over 7 days,high APACHE-Ⅱscore,poor sedation effect and elevated serum Cor,5-HT and INF-γ.