| 急性混合细胞白血病临床特征分析 |
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| 引用本文： | 闫轶鹏. 急性混合细胞白血病临床特征分析[J]. 医药论坛杂志, 2010, 0(5) |
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| 作者姓名： | 闫轶鹏 |
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| 作者单位： | 新乡医学院第一附属医院血液科; |
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| 摘 要： | 目的探讨急性混合细胞白血病的临床特征及诊治。方法根据骨髓细胞形态学、细胞化学染色和免疫表型结果诊断急性混合细胞白血病,采用DVCP方案、DVLP方案或DOAP方案化疗并根据骨髓缓解的情况评价疗效。结果11例患者临床表现为头晕乏力伴低热、胸骨压痛、淋巴结肿大、脾大、肝大、皮肤浸润等,所有患者骨髓增生明显活跃,近半数患者属高白细胞白血病。10例患者进行了免疫表型分析,其中B-Ly+/My+双表型8例、T-Ly+/My+双表型和B+T-Ly+/My+型各1例。采用DVCP方案、DVLP方案化疗7例,CR率42.9%,4例采用DOAP方案化疗,CR率50.0%。结论急性混合细胞白血病以B淋巴细胞系和髓系两系抗原共同表达者最多,临床分型诊断复杂,治疗缓解率低,预后差。
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| 关 键 词： | 急性混合细胞白血病 免疫表型 临床特征 诊断 化疗 预后 |
Clinical Characteristics Analysis of Acute Mixed Lineage Leukemia |
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| YAN YipengThe First Hospital of Xinxiang Medical College,Weihui ,China. Clinical Characteristics Analysis of Acute Mixed Lineage Leukemia[J]. Journal of Medical Forum, 2010, 0(5) |
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| Authors: | YAN YipengThe First Hospital of Xinxiang Medical College Weihui China |
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| Affiliation: | YAN YipengThe First Hospital of Xinxiang Medical College,Weihui 453100,China |
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| Abstract: | Objective To explore the clinical characteristics and treatment of acute mixed lineage leukemia.Methods According to the marrow cell morphology,cell chemical dyeing and immune phenotype to diagnose acute mixed lineage leukemia,using DVCP scheme,DVLP scheme or DOAP scheme and evaluating therapeutic efficiency according to the situation of marrow remission.Results The clinical manifestations of 11 patients were dizzy and tired with low-heat,sternal tenderness,lymph node enlargement,splenomegaly,hepatomegaly,s... |
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| Keywords: | Acute mixed lineage leukemia Immune phenotype Clinical characteristics Diagnosis Chemotherapy Prognosis |
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