双唑泰栓联合转移因子治疗复发性外阴阴道假丝酵母菌病 |
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引用本文: | 刘淑秋,吕淑莲. 双唑泰栓联合转移因子治疗复发性外阴阴道假丝酵母菌病[J]. 实用临床医学(江西), 2014, 0(6): 76-78 |
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作者姓名: | 刘淑秋 吕淑莲 |
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作者单位: | 鹤山市人民医院妇产科,广东 鹤山529700 |
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摘 要: | 目的:探讨双唑泰栓联合转移因子治疗复发性外阴阴道假丝酵母菌病(RVVC)的疗效及安全性。方法将240例RVVC患者按随机数字表法分为治疗组(予双唑泰栓+转移因子胶囊治疗)和对照组(予双唑泰栓治疗),7 d为一疗程,共两疗程,随访3个月。观察2组的临床疗效、不良反应及复发率。结果治疗组总有效率为92.7%,明显高于对照组的81.0%(P〈0.05)。治疗组Sobel 评分、复发率均低于对照组(P〈0.01)。2组不良反应轻微且差异无统计学意义(P〉0.05)。结论双唑泰栓联合转移因子治疗RVVC安全有效,能明显降低复发率。
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关 键 词: | 外阴阴道假丝酵母菌病,复发性 双唑泰栓 转移因子胶囊 疗效 |
Metronidazole Clotrimazole and Chlorhexidine Acetate Suppositories Combined with Transfer Factor Capsules for Recurrent Vulvovaginal Candidiasis |
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Affiliation: | LIU Shu-qiu, LU Shu-lian (Department of Gynaecology and Obstetrics, Heshan People's Hospital, Heshan 529700, China) |
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Abstract: | Objective To investigate the efficacy and safety of metronidazole clotrimazole and chlorhexidine acetate(MCCA)suppositories combined with transfer factor(TFC)capsules in the treatment of recurrent volvovaginal candidias (RVVC). Methods A total of 240 RVVC patients were randomly treated with MCCA suppositories alone (control group)or in combination with TFC capsules (treatment group) for two weeks. All patients were followed up for 3 months. Clinical efficacy, adverse events and recurrence rate were compared between the two groups. Results Compared with control group, TFC capsules significantly increased the total effective rate (92.7%vs 81.0%,P〈0.05)and obviously decreased Sobel score and recurrence rate(P〈0.01).Adverse reactions were mild in both groups and the differences were not significant between the two groups(P〉0.05). Conclusion MCCA combined with TFC is a safe and effective treatment and can reduce the recurrence rate in RVVC. |
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Keywords: | recurrence vulvovaginal candidiasis metronidazole clotrimazole and chlorhexidine acetate transfer factor capsules efficacy |
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