| 妊高征血清催乳素水平变化 |
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| 关 键 词： | 催乳素 放射免疫测定法治 妊娠高血压综合征 |
Prolactin in normal pregnancy and severe pregnancy-induced hypertension] |
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| Authors: | B L Chen Z H Zhang N B Liu K S Huang |
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| Institution: | Department of Obstetrics and Gynecology, Xiangya Hospital, Hunan Medical College, Central South University, Changsha 410008. |
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| Abstract: | OBJECTIVE: This study was to investigate the relationship between serum prolactin and pregnancy-induced hypertension. METHOD: Maternal serum prolactin was estimated by radioimmunoassay in 89 normal pregnant women and 52 patients with severe pregnancy-induced hypertension at 28 to 42 week gestation. RESULTS: In normal pregnancy, prolactin level increased progressively from a mean value of 270 mg.L-1 in the 24th week to 440 mg.L-1 in the 34th week and decreased progressively from the 38th week to the 40th week. In severe pregnancy-induced hypertension increased progressively too; 31 of 52 patients with severe prolactin showed high prolactin levels in zone A (> mean value + standard of prolactin values in the normal pregnancy), 10 patients in zone B (mean + standard to mean) and 11 patients in zone C (< mean). CONCLUSION: These results suggest that high prolactin levels may play an important role in the pathogenesis of severe pregnancy-induced hypertension. |
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