| 腹部外科手术后MODS患者内分泌及免疫功能的改变 |
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| 引用本文： | 王振文,尤胜义,王鹏志. 腹部外科手术后MODS患者内分泌及免疫功能的改变[J]. 临床外科杂志, 2008, 16(3): 184-186 |
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| 作者姓名： | 王振文 尤胜义 王鹏志 |
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| 作者单位： | 天津经济技术开发区医院外科,300457;天津医科大学总医院 |
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| 摘 要： | 目的 探讨腹部外科手术后MODS患者内分泌及免疫功能的改变。方法检测MODS组20例及非MODS组34例患者术前及术后1、3、7d外周血清TNF，IL-6，T3，T4，rT3，FT3，FT4，GH，C3，C4，CRP水平，进行统计学分析。结果MODS患者内分泌及免疫功能的改变大于非MODS患者。T3，T4，FT3，FT4较非MODS组显著性下降（P〈0．05），rT3，GH较非MODS组显著性升高（P〈0．05）。TNF，IL-6，CRP较非MODS组显著性升高（P〈0．05）。C3，C4较非MODS组显著性下降（P〈0．05）。结论MODS状态下出现的内环境紊乱，不仅有免疫失衡，神经及内分泌功能也有不同程度的改变。
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| 关 键 词： | 多脏器功能障碍综合征 内分泌 免疫 |
| 文章编号： | 1005-6483（2008）03-0184-03 |
| 收稿时间： | 2007-11-21 |
| 修稿时间： | 2007-11-21 |
Changes of endocrine and immunity in MODS patients undergoing abdominal surgical operations |
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| WANG Zhen-wen,YOU Sheng-yi,WANG Peng-zhi. Changes of endocrine and immunity in MODS patients undergoing abdominal surgical operations[J]. Journal of Clinical Surgery, 2008, 16(3): 184-186 |
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| Authors: | WANG Zhen-wen YOU Sheng-yi WANG Peng-zhi |
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| Affiliation: | WANG Zhen-wen, Y0U Sheng-yi, WANG Peng-zhi. ( Department of General Surgery, TEDA Hospital, Tianjin 300457, China) |
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| Abstract: | Objective To research the changes of endocrine and immunity in MODS patients after abdominal surgical operations.Methods Fifty-four subject to abdominal surgical operations were selected and divided into MODS group and control group.The levels of serum TNF,IL-6,T3,T4,rT3,FT3,FT4,GH,C3,C4 and CRP were determined before and after operation (1st,3rd,7th day).Results T3,T4,FT3,FT4,C3 and C4 levels were significantly reduced in MODS group as compared with those in control group (P<0.05).rT3,GH,TNF,IL-6 and CRP were increased significantly in MODS group as compared with control group (P<0.05).Conclusion There was internal enviroment disorder in MODS,which included changes of endocrine system and immune system. |
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| Keywords: | MODS endocrine immunity |
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