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Acute disseminated encephalomyelitis (ADEM) or ADEM-like inflammatory changes in a heart-lung transplant recipient: a case report |
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| Authors: | M B Horowitz C Comey W Hirsen D Marion B Grifith J Martinez |
| Institution: | (1) Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA;(2) Department of Radiology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA;(3) Department of Surgery, Division of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA;(4) Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA;(5) Present address: Department of Neurosurgery and Radiology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd., 75235 Dallas, TX, USA |
| Abstract: | Acute disseminated encephalomyelitis (ADEM) is a white matter inflammatory disease which usually follows a viral infection or pharmaceutical intervention. We describe a case of presumed ADEM in a heart/lung transplant patient, the etiology of which cannot be elucidated. The fascinating aspect is the mode of clinical presentation and the rapid resolution of radiologic abnormalities. Histologic examination of the brain is provided in an attempt to elucidate the radiographic abnormalities. |
| Keywords: | Acute disseminated encephalomyelitis Transplantation Magnetic resonance imaging FK-506 Rabbit antithymocyte globulin |
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