对比观察SWI与常规T1WI、T2WI、T2*WI显示肝硬化铁沉积结节的价值

目的评价SWI对肝硬化铁结节(SN)的检出率及其图像质量和检出结节数量,并与常规T1WI、T2WI、T2*WI对比。方法 128例肝硬化患者接受MR T1WI、T2WI、T2*WI和SWI。2名高年资放射科医师在SPIN图像处理软件上分别计算并比较4种图像上的SN检出率、SN与周围肝实质的信号强度比(SIR)、CNR,并计算SN的数量。结果 MR T1WI、T2WI、T2*WI和SWI的SN检出率分别为12.50%(16/128)、24.22%(31/128)、41.41%(53/128)和62.50%(80/128),SIR分别为0.85±0.16、0.58±0.17、0.50±0.20和0.36±0.21,CNR分别为9.15±5.79、9.77±5.49、11.49±4.57和13.93±5.64,SN的数量分别为(2.56±1.39)个/例、(16.27±12.32)个/例、(42.95±28.32)个/例和(72.31±62.99)个/例。SWI对SN的检出率明显高于T1WI、T2WI、T2*WI(χ2=26.86,P<0.05),SWI的SIR和CNR明显优于T1WI、T2WI、T2*WI(P均<0.05),SWI检出的SN数量明显多于T1WI、T2WI、T2*WI(P均<0.05)。结论 SWI在图像质量和SN的检出率以及检出数量上优于常规T1WI、T2WI和T2*WI,是检查肝硬化患者SN最敏感的方法,也是常规MR扫描的有益补充。

Comparison of SWI with T1WI, T2WI and T2*WI in detecting liver siderotic nodules in patients with liver cirrhosis

Objective To investigate the diagnostic performance of SWI for detecting siderotic nodules(SN) in patients with liver cirrhosis,and to compare SWI with T1WI,T2WI and T2*WI.Methods A total of 128 patients with chronic liver cirrhosis underwent MR T1WI,T2WI,T2*WI and SWI.The detection rate and number of SN,signal intensity ratio(SIR),and CNR were evaluated by two senior radiologists independently on SPIN software and were compared with T1WI,T2WI,T2*WI and SWI.Results The detection rate of SN with SWI(80/128,62.50%) was higher than that with MR T1WI(16/128,12.50%),T2WI(31/128,24.22%),T2*WI(53/128,41.41%)(χ2=26.86,P<0.05),respectively.SIR of SWI(0.36±0.21) was lower than that of T1WI(0.85±0.16),T2WI(0.58±0.17),T2*WI(0.50±0.20,P<0.05),respectively.CNR of SWI(13.93±5.64) was higher than that of T1WI(9.15±5.79),T2WI(9.77±5.49),T2*WI(11.49±4.57,all P<0.05),respectively.The number of SN with SWI(72.31±62.99) was higher than that with T1WI(2.56±1.39),T2WI(16.27±12.32),T2*WI(42.95±28.32,all P<0.05),respectively.Conclusion The imaging quality and detection rate for SN on SWI is higher than conventional MRI.SWI appears to provide the most sensitive method to detect SN in cirrhotic liver.It is a valuable complement to conventional liver MRI.