| 乌鲁木齐地区婴幼儿腹泻轮状病毒分子流行病学研究 |
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| 引用本文： | 李玉静,杨学磊,罗新辉,李奇凤,贾娜尔. 乌鲁木齐地区婴幼儿腹泻轮状病毒分子流行病学研究[J]. 中国病原生物学杂志, 2011, 0(9) |
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| 作者姓名： | 李玉静 杨学磊 罗新辉 李奇凤 贾娜尔 |
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| 作者单位： | 石河子大学医学院;新疆维吾尔自治区人民医院; |
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| 基金项目： | 国家自然科学基金项目(No.30760232); 益普生腹泻研究基金项目(No.IDF-2007-12) |
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| 摘 要： | 目的了解乌鲁木齐地区婴幼儿轮状病毒腹泻流行情况。方法收集新疆自治区人民医院2007年1～12月住院和门诊0～60月龄婴幼儿腹泻标本376份,ELISA筛查轮状病毒(RV),用RT-PCR对RV毒株进行基因分型。结果共检测376份标本,轮状病毒阳性181份,阳性率48.14%。感染者主要为出生24个月以内的婴幼儿(占98.34%)。9～10月为RV腹泻流行高峰。对161份阳性标本进行G/P基因分型,G1型是主要优势株,占31.68%,其次为G9型(21.12%)、G3型(15.53%)和G2型(14.91%),混合G型感染占14.29%,4例(2.48%)未能分型;P基因型以P[8]为主,占46.58%,其次为P[6](18.63%)、P混合感染(18.01%)和P[4](14.91%),3例(1.86%)未能分型;常见G/P组合G1P[8](24.84%)。结论轮状病毒是乌鲁木齐地区婴幼儿腹泻的主要病原,2007年G1P[8]是主要流行株,G9型成为本地区的第二大优势株。
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| 关 键 词： | 轮状病毒 基因型 腹泻 婴幼儿 |
Molecular epidemiology of rotavirus infection in infants and children with diarrhea in Urumqi |
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| LI Yu-jing,YANG Xue-lei,LUO Xin-hui,LI Qi-feng,JIA Na-er. Molecular epidemiology of rotavirus infection in infants and children with diarrhea in Urumqi[J]. Journal of Pathogen Biology, 2011, 0(9) |
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| Authors: | LI Yu-jing YANG Xue-lei LUO Xin-hui LI Qi-feng JIA Na-er |
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| Affiliation: | LI Yu-jing1,YANG Xue-lei2,LUO Xin-hui2,LI Qi-feng2,JIA Na-er2(1.Shihezi University Medical College,Shihezi City 832000,Xinjiang,China,2.People's Hospital of Xinjiang Uighur Autonomous Region,Urumqi 830001,China) |
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| Abstract: | Objective To investigate characteristics of rotavirus infection among infants and children with diarrhea in Urumqi.Methods Three hundred and seventy-six fecal samples were collected from infants and children ages 1 to 60 months who were seen by or hospitalized at the People's Hospital of Xinjiang Uighur Autonomous Region for diarrhea from January to December 2007.Samples were examined for rotavirus using ELISA.G/P genotypes of rotavirus strains were confirmed by RT-PCR.Results Rotavirus was detected in 181 ... |
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| Keywords: | Rotavirus genotype diarrhea children |
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