米索前列醇联合缩宫素预防产后出血的疗效分析

目的探讨米索前列醇联合缩宫素预防产后出血的临床疗效。方法选择我院2009年1月至2011年1月分娩的产妇123例,随机分为观察组和对照组。对照组患者在胎儿娩出后即刻静脉注射缩宫素10 U;观察组患者在对照组的用药基础上,同时采用米索前列醇0.4 mg直肠给药。记录两组患者第三产程时间、产后24 h出血量。结果观察组第三产程时间、产后24 h出血量分别与对照组比较,差异有统计学意义(P<0.05)。结论米索前列醇联合缩宫素能够显著缩短第三产程时间,减少产后出血量,临床效果显著。

Analysis on the Effect of Misoprostol Combined with Oxytocin for the Prevention of Postpartum Hemorrhage

Objective To discuss the clinical effect of misoprostol combined with oxytocin for the prevention of postpartum hemorrhage.Methods 123 giving birth mothers from Jan.2009 to Jan.2011 were randomly divided into observation group and control group.The control group were given 10 U of intravenous oxytocin immediately after the delivery;and the observation group were given 0.4mg misoprostol rectally on the basis of the control group.The time of third stage of labor and bleeding volume in 24h were recorded.Results The difference of the time of third stage of labor and bleeding volume in 24h between the two groups had statistical significance(P<0.05).Conclusion The combination of misoprostol and oxytocin can obviously shorten the time of third stage of labor,and reduce the bleeding volume,with obvious clinical efficacy.