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RP-HPLC法比较青海不同产地红景天属药材中成分组成的差异性
引用本文:陈海娟,王慧春,张国燕,李园媛. RP-HPLC法比较青海不同产地红景天属药材中成分组成的差异性[J]. 亚太传统医药, 2012, 8(8): 31-33
作者姓名:陈海娟  王慧春  张国燕  李园媛
作者单位:青海师范大学生命与地理科学学院/青藏高原环境与资源教育部重点实验室,青海西宁,810008
摘    要:目的:通过研究青海不同产地、不同种的红景天原植物药材中红景天苷和没食子酸的组成成分差异,为全面评价青海红景天属药材质量提供依据。方法:通过反向高效液相色谱法对青海不同产地或不同种的14个红景天样品中红景天苷和没食子酸进行了定量分析,并计算分析各成分间的结构比。结果:不同品种、不同来源的红景天原植物药材中,红景天苷和没食子酸的含量及其组成成分的结构比有较大差异。结论:由于产地、品种的不同,红景天属原植物药材中成分的组成和结构比存在差异性;成分间的结构比的差异性可能是红景天药材药效差异的根本原因,红景天属药材的质量应该从成分量和结构比两方面进行严格控制。

关 键 词:红景天  红景天苷  没食子酸  反相高效液相色谱法

Determination of Two Active Ingredients in Qinghai Variety of Medicinal Rhodiola by RP-HPLC
Chen Haijuan , Wang Huichun , Zhang Guoyan , Li Yuanyuan. Determination of Two Active Ingredients in Qinghai Variety of Medicinal Rhodiola by RP-HPLC[J]. Asia-Pacific Traditional Medicine, 2012, 8(8): 31-33
Authors:Chen Haijuan    Wang Huichun    Zhang Guoyan    Li Yuanyuan
Affiliation:(School of Life and Geographical Science in Qinghai Normal University,Key Laboratory of Education Department of Environment and Resources on Qinghai-Tibetan Plateau, Xining 810008, China)
Abstract:Objective:To provide the foundation for reasonable utilization by analysing salidroside and gallic acid from five different kinds of Radix Rhodiola in different areas of Qinghai. Methods: The contents of salidroside and gallic acid from five different kinds of Radix Rhodiola in different areas of Qinghai was determined by RP-HPLC, and proportions between the constituent structure was analyzed. Results:There were significant differences in salidroside and gallic acid content and the proportions between the constitu-ent structure from different species. Conclusion : The difference of proportions between the constituent structure indicates the differ-ence of pharmacodynamic action.
Keywords:Radix Rhodiola  Salidroside  Gallic Acid  RP-HPLC
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