47例鼻咽未分化癌放射治疗

目的：报道鼻咽未分化癌放射治疗以及预后相关因素。方法：lpps年7月至1988年12月我院收治47例鼻咽未分化癌患者，全部病例均经病理学证实，其中男性36例，女性11例，平均年龄41．3岁，均用”CO治疗机外照射。结果：所有病人随访皆超过5年，其3、5、10年生存率分别为北．9％、29．8％、20％，死于1年以下者19例，占物．4％。结论：对鼻咽未分化癌，病期愈旱，疗效愈好，放疗剂量以价ho－75Gy／－8周为宜，在对原发灶和颈部转移灶施行放疗的同时，应考虑采用综合治疗，以预防远处转移和提高生存率。

Analysis of 47 Patients with Undifferentiated Nasopharyngeal Cancer Treated with Radiotherapy

Objective: To probe the relationship between radiotherapy and prognosis for undifferentiated nasopharyngeal cancer. Methods: 47 eases of undifferentialed nasopharyngeal cancer were treated in our hospitalfrom July 1975 to December 1988. All patients were proved histopathologycally. There were 36 male, 11 female. The average age of the patients was 41. 3 years old. All paients received 60Co external beam irradiation. Results:All patients were followed up for more than 5 years. The 3 -, 5 -, 10 - year survival rate was 48. 9%, 29. 8% and 20% respectively. Nineteen patients died within 1 year after radiotherapy.The mortality rate was 40. 4%. Conclusions: Prognostic factors for undifferetiated nasopharyngeal cancer treated with radiotherapy included: Clinical stage, regression of primary lesion and metastases in the neck during radiation therapy. The proposed total dose was 60 ~ 75 Gy/6 ~ 8 weeks. Combination of radiotherapy with other therapys is a better modality for undifferentiated nasopharyngeal. It could preventmetastasis and thus improve the survival of the patients.