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Animal study on the role of serotonin in depression
Authors:Haruo Nagayama   Kounosuke Tsuchiyama   Kenji Yamada  Jotaro Akiyoshi
Affiliation:

Department of Neuropsychiatry, Medical College of Oita, Oita, Japan

Abstract:1. In our series of experiments the role of serotonin in human depression was studied by using animal models of depression.

2. The results of these studies support the hypothesis that some types of human depression may be primarily due to an excessive transmission of serotonin at the synapse.

Keywords:animal model   antidepressants   depression   8-OH-DPAT   serotonin
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