| 多囊卵巢综合征患者妊娠期胰岛素抵抗及妊娠结局观察分析 |
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| 引用本文： | 王蕴慧,张留苗,陈丽,张建平,刘颖琳,张睿. 多囊卵巢综合征患者妊娠期胰岛素抵抗及妊娠结局观察分析[J]. 中国实用妇科与产科杂志, 2011, 0(2) |
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| 作者姓名： | 王蕴慧 张留苗 陈丽 张建平 刘颖琳 张睿 |
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| 作者单位： | 中山大学孙逸仙纪念医院妇产科; |
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| 摘 要： | 目的探讨多囊卵巢综合征(PCOS)患者妊娠期胰岛素抵抗的变化及与妊娠结局的关系。方法选择2007年9月至2009年2月在中山大学孙逸仙纪念医院妇产科确诊为PCOS并妊娠成功的102例孕妇为PCOS组,同期在本院早孕检查、产检及分娩的普通孕产妇701例为对照组,比较两组孕妇的妊娠并发症及妊娠结局。对PCOS组中的38例及对照组中的50例孕妇于24～28周进行75g葡萄糖耐量检查及胰岛素释放试验,计算胰岛素抵抗指数(HOMA-IR)、胰岛β细胞分泌功能指数(HOMA-β)、血糖和胰岛素曲线下面积。结果 PCOS组血糖曲线下面积及胰岛素曲线下面积大于对照组(22.22±4.48、19.29±3.19,228.93±130.05、155.62±69.54,P<0.05);PCOS组空腹血糖、空腹胰岛素、HOMA-IR、HOMA-β大于对照组,分别为4.61±0.57、4.56±0.39,7.81±4.65、6.35±4.45,1.65±1.08、1.31±0.95,169.47±119.4、126.94±85.81,但差异无统计学意义。PCOS组与对照组妊娠并发症发生率分别为自然流产23.53%、8.27%,妊娠期糖...
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| 关 键 词： | 多囊卵巢综合征 胰岛素抵抗 流产 糖尿病 妊娠 妊娠结局 |
Insulin resistance and pregnancy outcome in women with polycystic ovary syndrome |
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| WANG Yun-hui,ZHANG Liu-miao,CHEN Li,ZHANG Jian-ping,LIU Ying-lin,ZHANG Rui. Insulin resistance and pregnancy outcome in women with polycystic ovary syndrome[J]. Chinese Journal of Practical Gynecology and Obstetrics, 2011, 0(2) |
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| Authors: | WANG Yun-hui ZHANG Liu-miao CHEN Li ZHANG Jian-ping LIU Ying-lin ZHANG Rui |
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| Affiliation: | WANG Yun-hui,ZHANG Liu-miao,CHEN Li,ZHANG Jian-ping,LIU Ying-lin,ZHANG Rui.Department of Obstetrics and Gynecology,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 510120,China |
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| Abstract: | Objective To approach the alteration of insulin resistance in pregnant women with polycystic ovary syndrome(PCOS) and the relationship with pregnancy outcomes.Methods Between Sep.2007 and Feb.2009,One hundred and two pregnant women with PCOS diagnosed in the second affiliated hospital,Sun Yat-sen University were PCOS group,at the same time 701 normal pregnant women were selected as control group.The complication and pregnancy outcome were compared between the two groups.At equal pace,38 pregnant women in PC... |
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| Keywords: | polycystic ovary syndrome insulin resistance spontaneous abortion gestational diabetes mellitus pregnancy outcome |
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