甲状旁腺功能减退症的颅脑CT特征分析

目的探讨甲状旁腺功能减退症的颅脑CT表现及临床特点。方法对经临床确诊的甲状旁腺功能减退症11例患者进行颅脑CT平扫，将其cT表现进行分析。结果本组患者颅脑cT扫描均发现脑内有不同程度钙化，主要分布于双侧基底节区、丘脑、小脑齿状核、灰白质交界区及半卵圆中心，基底节区钙化为逗点状、三角形及倒八字形，丘脑钙化为斑点状，小脑齿状核钙化为肾形、片状，灰白质交界区钙化为钩子状，半卵圆中心钙化呈横行排列，而双侧内囊区未累及。脑内钙化部位频数依次为苍白球和壳核11例，丘脑10例，尾状核头部8例，小脑齿状核7例，额顶叶6例，半卵圆中心4例，枕叶2例。结论甲状旁腺功能减退症颅脑cT表现具有特征性，可为临床诊断提供可靠的影像学依据，结合低血钙、高血磷、甲状旁腺激素水平降低实验室检查即可明确诊断．

An analysis of characteristics of hypoparathyrodism in cranial CT

Objective To investigate cranial CT manifestations and the clinical feature of hypoparathyroidism. Methods To examine the 11 cases of hypoparathyroidism patients by cranial CT scanning, and analyze the charac- teristics of CT findings. Results The calcification of different degree was found in the brain of patients by CT scan- ning,which mainly distributed in bilateral basal ganglia, cerebral ganglia, dentate body of cerebellum, the gray-white matter junction and semivale center. The shape of calcification in basal ganglia was comma-liked, trigonal and re- versed-splay, and it was speckled in the thalamus, kidney-shaped and flaky ineerebellar dentate nueleuse, hook- shaped in the gray-white matter junction,and lateropulsion-disposed in the semiovale center. But the region of bilater- al internal capsule was not involved. Intraeerebral calcification frequeney：l leases in globus pallidus and putament, 9 cases in cerebral ganglia; 8 cases in the head of caudat nucleus, 7 cases in dentate body of cerebellum, 6 cases in frontal and patietal loke, 4 cases in semiovale center, 2 cases in occipital loke. Conclusion The CT feature of hy- poparathyroidism is specific,which can provide reliable reference of clinical imageology, and when combine with laboratory examination, such as hypocalcemia, hyperphosphatemia, and low-level PTH, the diagnosis of hypoparathy- roidism can be confirmed.