A fast and accurate algorithm for volume determination in MRI.

The determination of volumes in clinical MRI studies are prohibitive because of the time required to compute an accurate volume. Techniques that speed up the calculation are prone to large errors which make most impractical for an accurate diagnosis. A linear filter, called the eigenimage filter, has been developed that separates a desired feature from other features which interfere with its observation in an image. Using the images produced by this technique (eigenimages), the amount of operator interaction required to calculate volumes are significantly reduced. The technique also has the ability to correct for partial volume averaging effects and as a result a more accurate volume can be determined. The technique was applied to a computer simulation and two phantom studies. The time required to calculate the volume was less than 1 min per slice and the errors in accuracy and reproducibility were less than 2% for all studies.