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高龄男性2型心肾综合征患者血清睾酮水平的研究
引用本文:边瓯,马宁,乔锐,任奕,丁亮,何瑞.高龄男性2型心肾综合征患者血清睾酮水平的研究[J].国际心血管病杂志,2014(5):350-352.
作者姓名:边瓯  马宁  乔锐  任奕  丁亮  何瑞
作者单位:沈阳军区总医院干部病房一科, 辽宁,110016
摘    要:目的:观察高龄男性2型心肾综合征患者血清睾酮水平的变化。方法:入选年龄≥75岁的慢性心力衰竭男性患者150例,将其中2型心肾综合征者设为观察组(n=69),其余设为对照组(n=81)。检测并比较两组患者血清睾酮、胱抑素-C、N末端B型利钠肽原(NT-proBNP)、超敏C反应蛋白等指标。结果:观察组血清胱抑素-C、NTproBNP、超敏C反应蛋白水平均高于对照组(P〈0.05)而血清睾酮水平显著低于对照组,为(12.7±6.08)nmol/L对(22.07±7.53)nmol/L,P〈0.01;其余指标组间均无统计学差异。结论:高龄男性慢性心力衰竭患者中,发生2型心肾综合征者血清睾酮水平降低。

关 键 词:血清睾酮  高龄  男性  2型心肾综合征

Serum testosterone ievei in eideriy maie patients with type 2 cardiorenai syndrome
BIAN Ou,MA Ning,QIAO Rui,REN Yi,DING Liang,HE Rui.Serum testosterone ievei in eideriy maie patients with type 2 cardiorenai syndrome[J].International Journal of Cardiovascular Disease,2014(5):350-352.
Authors:BIAN Ou  MA Ning  QIAO Rui  REN Yi  DING Liang  HE Rui
Institution:. (First Cardre Department, General Hospital of Shenyang Military Command, Liaoning 110016, China)
Abstract:Objective:To observe the change of serum testosterone levels in elderly male patients with type 2 cardiorenal syndrom (CRS). Methods:A total of 150 male patients with chronic heart disease over the age of 75 selected into this study were assigned to observation group (type 2 CRS,69 cases)and control group (non-type 2 CRS,81 cases).Serum testosterone,cystatin-C,N-terminal pro-brain natriuretic peptide (NT-proBNP),high sensitivity C-reactive protein (hs-CRP)and some other serological indexes were determined. Resuits:The serum levels of cystatin-C,NT-proBNP and hs-CRP were all higher (P 〈0.05),but serum testosterone was significantly lower(12.7 ±6.08)nmol/L vs. (22.07±7.53)nmol/L,P 〈0.01 ]in observation group than those in control group. Conciusion:The serum testosterone level may decrease in elderly male patients with type 2 CRS.
Keywords:Testosterone  Elderly  Male  Type 2 cardiorenal syndrome
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