| 慢性乙型肝炎病毒感染者胃黏膜、胃液及血清中乙肝病毒标志物相关性研究 |
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| 引用本文： | 庞念德,陈安海. 慢性乙型肝炎病毒感染者胃黏膜、胃液及血清中乙肝病毒标志物相关性研究[J]. 贵州医药, 2011, 35(4). DOI: 10.3969/j.ISSN.1000-744X.2011.04.009 |
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| 作者姓名： | 庞念德 陈安海 |
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| 作者单位： | 1. 深圳市盐田区人民医院,518000
2. 遵义医学院,563003 |
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| 摘 要： | 目的通过研究慢性乙型肝炎病毒感染者胃液、胃黏膜及血清中乙型肝炎病毒标志物的存在情况,分析它们之间的相互关系,以探讨乙型肝炎病毒感染对慢性乙型肝炎病毒感染者胃黏膜病变的影响及乙型肝炎病毒消化道传播的可能性。方法对60例慢性乙型肝炎病毒感染者同时行胃镜检查,用酶联免疫吸附法(ELISA)检测胃液、血清中HBsAg、HBeAg、anti-HBs、anti-HBe、anti-HBc,免疫组织化学法(Envision)检测胃黏膜组织中HBsAg、HBcAg。结果 60例慢性乙型肝炎病毒感染者胃液中HBsAg、HBeAg的检出率分别为80.0%、25.0%。其胃液中的HBsAg、HBeAg与血清中HBsAg、HBeAg之间无统计学意义(P>0.05),部分血清中HBsAg、HBeAg阴性者,胃液中HBsAg、HBeAg出现阳性。60例慢性HBV感染者胃黏膜组织中HBsAg和(或)HBcAg阳性29例,在胃黏膜组织中单项HBsAg阳性2例,单项HBcAg阳性10例,同时阳性17例,胃黏膜中HBsAg、HBcAg与血清中的HBVM比较,无统计学意义。60例慢性HBV病毒感染者中29例胃黏膜组织中可检测到HBsAg和(或)HB...
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| 关 键 词： | 胃黏膜 胃液 乙型肝炎病毒标志物 |
Relationships among Hepatitis B Virus markers in gastric juice,serum and gastric mucosa in chronic patients with hepatitis B virus infection |
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| Pang Niande,Chen Anhai. Relationships among Hepatitis B Virus markers in gastric juice,serum and gastric mucosa in chronic patients with hepatitis B virus infection[J]. Guizhou Medical Journal, 2011, 35(4). DOI: 10.3969/j.ISSN.1000-744X.2011.04.009 |
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| Authors: | Pang Niande Chen Anhai |
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| Affiliation: | 1.Yantian District People s Hospital Of Shenzhen.2.The Affiliated Hospital of Zunyi Medical College; Zunyi 563003; China; |
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| Abstract: | Objective To investigate the correlation among hepatitis B virus markers(HBVM) in gastric juice,serum and gastric mucosa in chronic patients with hepatitis B virus infection.The influence of HBV infection on gastric mucosa in chronic hepatitis B patients,and the possibility of infection by alimentary canal.Methods All patients were undertaken gastroscopy.HBVM in serum and gastric juice were determined with ELISA while HBsAg and HBcAg in gastric mucosa were detected by immunohistochemistry.Results The positi... |
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| Keywords: | Gastric mucosa Gastric juice Hhepatitis B Virus markers |
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