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广州市斯氏屋顶鼠对第一代抗凝血灭鼠剂抗药性初步研究
引用本文:易建荣,段金花,林立丰,张世炎,梁练,阴伟雄.广州市斯氏屋顶鼠对第一代抗凝血灭鼠剂抗药性初步研究[J].中国媒介生物学及控制杂志,2009,20(4):317-318.
作者姓名:易建荣  段金花  林立丰  张世炎  梁练  阴伟雄
作者单位:1. 广东省疾病预防控制中心消毒杀虫研究所,广州,510300
2. 广东省湛江鼠疫防治研究所
基金项目:广东省医学科学研究基金 
摘    要:目的探讨斯氏屋顶鼠对抗凝血灭鼠剂的抗药性变化。方法参照全国鼠类抗药性监测协作组统一方法,进行无选择性摄毒试验。结果经对广州市所辖9个区内所捕获的53只斯氏屋顶鼠进行抗药性监测,存活率为3.8%,其总平均摄药剂量为30.31mg/kg,存活平均摄药剂量为58.29mg/kg。经与同期同地家栖鼠抗药性比较,该鼠种对第一代抗凝血灭鼠剂敏感性介于黄胸鼠与褐家鼠之间。结论控制斯氏屋顶鼠可使用第一代抗凝血灭鼠剂,但应加强对灭鼠药物的敏感性监测,科学、合理用药。

关 键 词:斯氏屋顶鼠  抗凝血灭鼠剂  杀鼠灵  抗药性

Primary study on the resistance of Rattus rattus sladeni to anticoagulant rodenticide in Guangzhou
YI Jian-rong,DUAN Jin-hua,LIN Li-feng,ZHANG Shi-yan,LIANG Lian,YIN Wei-xiong.Primary study on the resistance of Rattus rattus sladeni to anticoagulant rodenticide in Guangzhou[J].Chinese Journal of Vector Biology and Control,2009,20(4):317-318.
Authors:YI Jian-rong  DUAN Jin-hua  LIN Li-feng  ZHANG Shi-yan  LIANG Lian  YIN Wei-xiong
Institution:YI Jian-rong, DUANJin-hua, LIN Li-feng, ZHANG Shi-yan, LIANG Lian, YIN Wei-xiong. (Guangdong Center for Disease Control and Prevention, Guangzhou, Guangdong 510300, China)
Abstract:Objective To study the resistance of Rattus rattus sladeni to anticoagulant rodenticide. Methods No-choice food test was used in this study according to the method of national rodent resistance surveillance group. Results The rodents caught in nine districts of Guangzhou were tested. The survival rate was 3.8%. The total average dosage was 30.31 mg/kg, and survival average dosage was 58.29 mg/kg. The result showed that its sensitivity to anticoagulant rodenticide was between R.tanezumi and R.norvegicus. Conclusion The anticoagulant rodenticide can be still used to the control ofR.rattus sladeni. But it should strengthen the resistance surveillance, and the chemicals should be used scientifically and rationally.
Keywords:Rattus rattus sladeni  Anticoagulant rodenticide  Warfarin  Resistance
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