妇科恶性肿瘤化疗患者262例血糖观察

目的 观察化疗对妇科恶性肿瘤患者血糖的影响.方法 回顾性分析我科收治的262例恶性肿瘤患者化疗前、中、后糖尿病的发生情况,对并发糖尿病患者进行随访.结果 化疗后空腹血糖升高24例,糖尿病8例,糖耐量减低11例,一过性血糖升高5例.PT方案化疗较PVB方案化疗更易引起血糖增高(P＜0.05).结论 恶性肿瘤患者化疗后可引起血糖增高,甚至发生糖耐量减低或2型糖尿病.Abstract：Objective To explore the effect of chemotherapy on glucose metabolism in patients with gynecological malignant tumor.Methods Two hundred and sixty -two patients with gynecological malignant tumor who treated with chemotherapy were analyzed retrospectively.The incidence of diabetes mellitus as analyzed.The occurrence of diabetes before, during and after chemotherapy for patients with malignant tumors was observed.Results Total 24 cases had elevated fasting blood glucose after chemotherapy.Among them ,8 cases were diagnosed as diabetes mellitus, 11 cases were diagnosed as impaired glucose tolerance.Significant difference of blood glucose was observed between patients treated with PT chemotherapy and those who treated with PVB chemotherapy(P ＜ 0.05).Conclusions Chemotherapy could make the blood glucose of patients with malignant tumor increase, and may result in decreased sugar tolerance or type 2 diabetes.

Change of blood glucose in 262 patients with gynecological malignant tumor received chemotherapy

Gynecological malignant tumor Chemotherapy Blood glucose