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熊去氧胆酸治疗慢性乙型肝炎患者γ-谷氨酰转肽酶升高的疗效观察
引用本文:梁红霞,潘延凤,余祖江,张贤强,江河清,Hong-xia,Yan-feng,Zu-jiang,Xian-qiang,He-qing.熊去氧胆酸治疗慢性乙型肝炎患者γ-谷氨酰转肽酶升高的疗效观察[J].中原医刊,2010(9).
作者姓名:梁红霞  潘延凤  余祖江  张贤强  江河清  Hong-xia  Yan-feng  Zu-jiang  Xian-qiang  He-qing
摘    要:目的 探讨熊去氧胆酸治疗慢性乙型肝炎患者持续性γ-谷氨酰转肽酶(GGT)升高的疗效.方法 69例患者随机分为治疗组(35例)和对照组(34例),治疗组予以常规保肝治疗和熊去氧胆酸(UDCA)口服,对照组单独予以常规保肝治疗.分别检测两组治疗15 d和30 d时GGT的水平.结果 对照组和治疗组在治疗15 d和30 d时GGT值比较差异均有统计学意义(P<0.05).结论 熊去氧胆酸能快速、有效地降低慢性乙型肝炎患者持续升高的GGT. Abstract: Objective To investigate the effects of ursodeoxycholic acid on lowering continuously elevated gamma glutamyl transpeptidase(GGT) levels in patients suffering from chronic hepatitis B virus.Methods Patients in the treatment group were given conventional liver protecting treatment in combination with oral ursodeoxycholic acid therapy, in a dose of 250 mg twice a day.And patients in control group were given conventional liver protecting treatment.The GGT levels were detected on the 15th day and 30th day after treatment.Results There were significant differences of GGT levels between the treatment group and control group on the 15th day and 30th day affer therapy (P<0.05).Conclusions Ursodeoxycholic acid can lower the continuously elevated GGT levels in patients with chronic hepatitis B virus quickly and effectively.

关 键 词:熊去氧胆酸  常规保肝治疗  慢性乙型肝炎患者  谷氨酰转肽酶  升高  疗效观察  chronic  hepatitis  B  virus  GGT  ursodeoxycholic  acid  treatment  levels  conventional  治疗组  对照组  control  significant  differences  combination  统计学意义  比较差异

Effects of ursodeoxycholic acid on lowering GGT in patents with chronic hepatitis B virus
Abstract:Chronic hepatitis B virus Gamma glutamyl transpeptidase Ursodeoxycholic acid
Keywords:Chronic hepatitis B virus    Gamma glutamyl transpeptidase    Ursodeoxycholic acid
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