异位妊娠影响因素的对照研究

目的探讨异位妊娠发生的影响因素，为预防异位妊娠的发生提供理论参考依据。方法采用患者对照研究，选取2011年12月-2012年5月期间芜湖某两医院收治的71例异位妊娠患者作为病例组．按1：2的比例选取同期住院的142例正常妊娠者作为对照组，调查其既往生活习惯、婚育状况、疾病手术史和焦虑情况等。结果患者组和对照组的焦虑检出率分别为56．34％、20。42％，差异具有统计学意义（χ^2=27．88，P〈0．01）。多因素非条件Logistic回归分析显示焦虑（OR=6．08，P〈0．01）、妇科炎症史（OR=8．39，P〈0．01）、宫内节育器史（OR=6．92，P〈0．01）、流产史（OR=5．88，P=0．03）及被动吸烟（OR=6．58，P〈0．01）是导致异位妊娠发生的危险因素，月经规律（OR=0．28，P〈0．01）为保护性因素。结论对计划生育者进一步加大心理辅导力度，并开展与异位妊娠相关的孕期健康教育，能有效减少异位妊娠的发生几率。

A case-control study of ectopic pregnancy

Objective ] To explore the influential factors in ectopic pregnancy, and provide scientific evidence for its appropriate control and prevention. Methods ] A Case-control study was used. 71 patients with ectopic pregnancy who were admitted in two hospitals of Wuhu City from December 2011 to May 2012 were selected as case, and 142 normal pregnant women as control during the same period of hospitalization. The investigation included living habits, marital status, self-rating anxiety scale（SAS）, medical history. Results ] The detection rates of anxiety in case and control were 56.34% and 20.42%, respectively. There was significant statistically difference（χ^2=27.88, P〈0.01）. Multivariate unconditional logistic repression revealed that anxiety（OR=6.08, P〈0.01）, gynecological inflammation history（OR=8.39, P〈χ.01）, IUD history（OR=6.92, P〈0.01）, abortion history（OR=5.88, P=0.03） and passive smoking （OR=6.58, P〈0.01） were the risk factors for ectopic pregnancy, while, menstrual regularity （OR=0.28, P〈0.01） was the protective factor Conclusion ] The psychotherapy should be addressed besides appropriate symptomatic treatment and health education about ectopic pregnancy, which are interventions to improve their life quality and awareness of disease prevention.