血栓抽吸导管联合替罗非班治疗急性ST段抬高型心肌梗死的远期疗效分析

目的 研究血栓抽吸导管联合替罗非班治疗急性ST段抬高型心肌梗死的远期疗效.方法 选择我院2009年1月-2011年5月102例急性ST段抬高型心肌梗死患者,均于急诊行经皮冠状动脉介入（PCI）治疗.将应用血栓抽吸导管联合替罗非班治疗的61例患者作为观察组,未采用该方法治疗的41例患者作为对照组,所有患者均随访6-24个月,对治疗效果及远期疗效进行评价.结果 治疗后两组LVEF较治疗前明显提高,与治疗前比较差异有统计学意义（P＜0.05）;观察组治疗后和随访24个月,LVEF提高幅度均大于对照组,观察组心血管不良事件发生率为3.28％,明显低于对照组,两组比较差异有统计学意义（P＜0.05）.结论 血栓抽吸导管联合替罗非班治疗对改善急性ST段抬高型心肌梗死患者预后具有明显作用,且患者可在术后较长时间持续获益.

Long-Term Effect Analysis of Thrombus Suction Catheter Combined with Tirofiban Therapy in Patients with Acute ST Segment Elevation of Myocardial Infarction

Objective To study the long-term effect of thrombus suction catheter combined with tirofiban therapy in patients with acute ST segment elevation myocardial infarction. Methods 102 patients with acute ST segment elevation of myocardial infarction in our hospital from January 2009 to May 2011 were given percutaneous coronary intervention （PCD therapy. Observation group （61 cases） was given thrombus suction catheter combined with tirofihan therapy, 41 cases were the control group. All patients were followed up for 6 to 24 months, then evaluated the treatment effect and long-term curative effect. Results The LVEF of two groups after treatment were obviously improved,LVEF of two groups before and after treatment had statistic difference （P〈0.05）. The I.VEF increases in observation group after treatment and followed up for 24 months were higher than control group, the incidence of cardiovascular adverse events of observation group （3.28%） was lower than control group, the difference had statistic meaning （P〈0. 05）. Conclusion Thrombus suction catheter combined with tirofiban therapy has obvious effect on improving the prognosis of patients with acute ST segment elevation of myocardial infarction, and the beneficial effects can be lasted for a long period of time after treatment.