护肾愈消汤治疗早期糖尿病肾病38例的临床观察

目的：通过随机对照研究，观察护肾愈消汤治疗早期糖尿病肾病的临床疗效。方法：选择70例早期糖尿病肾痛患者，随机分为治疗组38例和对照组32例。两组均给予糖尿病基础治疗，对照组加用氯沙坦钾片，治疗组加用护肾愈消汤。治疗60天后，观察两组治疗前后FBG、2hPG、TC、TG、HDL—C、LDL—C及UAE等指标变化。结果：治疗后两组FBG、2hPG和UAE等指标均比治疗前后有显著下降（P〈0.01），治疗组UAE比对照组下降更明显，两组比较有显著性差异（P〈0．05）。治疗后治疗组TC、TG、LDL—C下降，对照组治疗前后无显著变化。治疗后治疗组TC、TG、LDL—C比对照组下降明显（P〈0．05）。结论：护肾愈消汤对早期糖尿痛肾病有确切疗效，该药具有降低尿微量白蛋白和血脂的作用。

Clinical Observation of Hushen Yuxiao Decoction for Treatment of 38 Cases of Early Diabetic Nephropathy

Objective： to observe therapeutic effects of Hushen Yuxiao Decoction for early stage diabetic nephropathy （DN） by randomized control study, Methods：70 early DN patients were randomly grouped to treated group （38 cases） and control group （32 cases）. In addition to basic hypoglycemic medication, the control group took losartan potassium and the treated group administered Hushen Yuxiao Decoction, Parameters investigated included FBG, 2hPG, TC, TG, HDL-C, LDL-C and UAE before and after sixty day-treatment. Results：FBG, 2hPG mid UAE levels of both groups significantly dropped （P 〈 0. 01 ） after treatment, and UAE level of the treated group was markedly lower compared with the control group （ P 〈 0. 05 ）, After treatment, TC, TG, LDL-C levels were lower in the treated group and no signific：ant reduction was seen for the control group, thus treated group significantly cut down these three levels in comparison with the control group （ P 〈 0. 05 ）, Conclusion： Early DN responds well to Hugan Yuxiao Decoction. The decoction is helpful to bring down microalubumin and blood fat