Experimental herpetic keratitis in the guinea pig |
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| Authors: | Gilbert Smolin Masao Okumoto Shigeaki Ohno |
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| Affiliation: | 1. The Francis I. Proctor Foundation for Research in Ophthalmology, University of California, San Francisco, California USA;2. the Department of Ophthalmology, University of California, San Francisco, California USA |
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| Abstract: | A model of herpetic keratitis with type 1 Herpesvirus hominis was established in the guinea pig. The administration of 10 mg triamcinolone acetonide subconjunctivally in both eyes resulted in an amelioration of the clinical course of the disease process, whereas 40 mg injected peritoneally did not. The possible pathophysiology of these responses is discussed. |
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| Keywords: | corticosteroids guinea pig herpetic keratitis immunologic response |
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