Differentiating solitary pulmonary metastases in patients with extrapulmonary neoplasmas using FDG-PET |
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Authors: | Hsu Wu-Huei Hsu Nan-Yung Shen Yeh-You Yen Ruoh-Fang Kao Chia-Hung |
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Institution: | Division of Pulmonary/Critical Care Medicine, China Medical College Hospital, No. 2, Yuh-Der Road, Taichung 404, Taiwan. |
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Abstract: | The purpose of this preliminary study is to evaluate the characteristics of solitary pulmonary lesions in patients using extrapulmonary neoplasmas with 18F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET). Thirty-two patients with extrapulmonary neoplasmas who had solitary pulmonary lesions and were suspected for pulmonary metastasis underwent an oncological survey with FDG-PET. Standard uptake value (SUV) and the ratio of lesion-to-background (L/B ratio) were used as parameters to differentiate and characterize the solitary pulmonary lesions. Using SUV > 2.5 or L/B ratio > 3 as the cutoff to diagnose malignancy, FDG-PET correctly identified 29 true-positive cases. However, FDG-PET failed to interpret two false-positive and one false-negative cases. The accuracy of FDG-PET was 91%. We concluded that FDG-PET is an accurate modality to differentiate solitary pulmonary lesions in patients with extrapulmonary neoplasmas. |
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