|
|||||
|
|
| 支气管肺泡灌洗液组织多肽抗原检测对肺癌诊断的价值 | |
| 引用本文： | 刘洪洲,齐景宪,张志贤.支气管肺泡灌洗液组织多肽抗原检测对肺癌诊断的价值[J].郑州大学学报(医学版),2002,37(2):190-191. |
| 作者姓名： | 刘洪洲 齐景宪 张志贤 |
| 作者单位： | 1. 濮阳市人民医院呼吸内科,濮阳,457000 2. 郑州大学第二附属医院呼吸内科郑州,450003 3. 濮阳市卫生学校濮阳,457000 |
| 摘 要： | 目的：探讨支气管肺泡灌洗液（BALF）中组织多肽抗原（TPA）含量对肺癌的诊断价值。方法：应用酶联免疫法检测60例初次确诊的肺癌和30例肺良性疾病患者BALF中TPA含量，并与血清中含量比较，采用ROC曲线确定BALF中TPA的阈值。结果：肺癌患者BALF中TP含量明显高于肺良性疾病患者（P＜0.05），BALF中TPA检测诊断肺癌的灵敏度为83.33%，特异度为86.67%。肺癌患者BALF中TPA含量显著高于血清中的含量（P＜0.01）。结论：BALF中TPA的检测对肺癌有较高的诊断价值。 |
| 关 键 词： | 肺肿瘤 组织多肽抗原 支气管肺泡灌洗液 诊断 肿瘤标志物 |
| 修稿时间： | 2001年7月24日 |
Determination of TPA in bronchoalveolar lavage fluid for patients with lung cancer |
|
| LIU Hongzhou ,QI Jingxian ,ZHANG Zhixian.Determination of TPA in bronchoalveolar lavage fluid for patients with lung cancer[J].Journal of Zhengzhou University: Med Sci,2002,37(2):190-191. | |
| Authors: | LIU Hongzhou QI Jingxian ZHANG Zhixian |
| Institution: | LIU Hongzhou 1),QI Jingxian 2),ZHANG Zhixian 3) 1)Department of Pulmonary Medicine,Puyang People's Hospital,Puyang 457000 2)Department of Pulmonary Medicine,the Second Affiliated Hospital,Zhengzhou University,Zhengzhou 450003 3)Pu |
| Abstract: | Aim:To investigate the diagnostic value of TPA determination in bronchoalveolar lavage fluid (BALF) for lung cancer.Methods:TPA levels were measured with enzyme linked immunosorbent assay(ELISA)in the BALF of 60 patients with lung cancer and 30 patients with benign lung diseases. The results were compared to those of serum TPA.The threshold value of TPA in BALF were determined by ROC curve.Results:Levels of TPA in BALF in patients with lung cancer were higher than those with benign lung diseases ( P <0 05) The sensitivity and specificity of TPA for diagnosing lung cancer were 83.33% and 86 67%,respectively.TPA levels in BALF in patients with lung cancer were significantly higher than those in serum.Conclusion:Determination of TPA in BALF can be used to diagnose lung cancer. |
| Keywords: | lung neoplasm tissue polypeptide antigen brochoalveolar lavage fluid |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |