雷米芬太尼复合丙泊酚麻醉应用于结肠镜检查临床观察

目的探讨雷米芬太尼复合丙泊酚用于结肠镜检查患者的麻醉效果。方法80例接受结肠镜检查患者(ASAⅠ~Ⅱ级)随机均分2组,观察组应用雷米芬太尼加丙泊酚麻醉,对照组应用芬太尼加丙泊酚麻醉,观察记录心率、血压及血氧饱和度的变化,并记录体动反应。结果2组麻醉前心率、收缩压、舒张压、血氧饱和度比较均无显著差异(P>0.05),2组收缩压、舒张压和心率(对照组诱导后1 min时心率除外)麻醉诱导后1 min、5 min、10 min、15 min时与麻醉前比较均有显著性差异(P<0.05),观察组收缩压、舒张压及心率在麻醉诱导后1 min、5 min、10 min、15 min时明显低于对照组(P<0.05,1 min时SBP除外),而2组血氧饱和度比较无显著性差异(P>0.05),观察组患者术中体动反应发生率明显低于对照组(P<0.05)。结论等效价强度雷米芬太尼复合丙泊酚的镇痛效果强于芬太尼复合丙泊酚,更适用于无痛结肠镜检查术。

Clinical observation of remifentanil combined with propofol in patients treated with coloscopy

Objective To evaluate clinical anaesthesia efficacy of remifentanil combined with propofol in patients treated with coloscopy.Methods Eighty ASA I-II patients after colonscopy were randomly divided into study groups(n=40)and control group(n=40).The study group were anesthetized by remifentanil combined with propofol;the control group by fentanyl combined with propofol.Variations of heart rate,blood presure,and saturation of blood oxygen were recorded,so were body dynamic responses.Results Before the anaesthesia,the systolic blood pressure(SBP),diastolic blood pressure(DBP),heart rate(HR) and saturation pulse oximeter(SpO2) of the two groups showed no statistically significance(P>0.05).One min,5 min,10 min,and 15 min after the anesthesia induction,SBP,DBP,and HR(HR of the control group 1min after the induction excepted) showed significant difference compared with those before the induction,respectively(P<0.05);SBP,DBP,and HR of the study group were significantly lower than those of the control group(P<0.05,SBP of 1 min excepted);saturations of blood oxygen of the two groups showed no significant difference;and the dynamic response of the study group was also better than that of the control group(P<0.05).Conclusion Remifentanil combined with propofol is an ideal narcotic analgesic treatment at the time of anesthesia induction and intubation and can shorten recovering time after operation.