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慢性应激对大鼠行为和体重的影响
引用本文:郑晖,杨权,吴彩茹. 慢性应激对大鼠行为和体重的影响[J]. 四川精神卫生, 2004, 17(2): 71-72
作者姓名:郑晖  杨权  吴彩茹
作者单位:515063,广东省汕头大学医学院精神卫生中心
摘    要:目的 观察慢性应激对大鼠行为和体重的影响。方法 采用慢性强迫游泳模型 ,应用行为追踪仪观察大鼠的活动量 ,以电子动物称监测大鼠体重变化。结果 应激组大鼠活动量明显高于对照组 (P <0 0 1) ,排便、排尿增加 ,修饰频繁。应激组大鼠体重增长明显低于对照组 (P <0 0 1)。结论 慢性强迫游泳使大鼠活动量增多 ,抑制体重增长。

关 键 词:应激 行为体重
文章编号:1007-3256(2004)02-0071-02

Effects of chronic stress on behavior and body weight of rats
ZHENG Hui,YANG Quan,WU Cairu. Effects of chronic stress on behavior and body weight of rats[J]. Sichuan Mental Health, 2004, 17(2): 71-72
Authors:ZHENG Hui  YANG Quan  WU Cairu
Affiliation:ZHENG Hui,YANG Quan,WU Cairu.Mental Health Center,Shantou University Medical College,Guangdong 515063,China
Abstract:Objective To observe the effects of chronic stress on behavior and body weight of rats.Methods Chronic forced-swimming was used as stress model.Behavioral detector was applied to observe motor activity;elctronic animal scale was used to weigh the rats.Results Motor activity in stress group was significantly higher than that in control group( P <0.01),the stressed rats showed more times of defecate and emiction and more modified behavior.Body weight gain in stress group was significantly lower than that in control group( P <0 01).Conclusion Chronic forced-swimming could increase motor activity and suppress weight gain of rats.
Keywords:Stress Behavior Body weight
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