通关藤及其制剂的药理作用和临床应用进展

通关藤含有三萜、甾醇、有机酸等化学成分,其活性成分主要为研究较多的C21甾体类化合物,而对其他成分的研究较少；现代药理研究表明,其具有较强的生物活性,在抗肿瘤、降压、平喘等方面有着显著作用.通关藤经提取制成的一系列药物制剂在临床上已得到广泛应用,其中消癌平注射液治疗癌症疗效较好.对近年来通关藤及其制剂的药理研究和临床应...

Advances in pharmacological effects and clinical application of Marsdenia tenacissima and its preparation

Marsdenia tenacissima is a Chinese medicine with antitumor effect, and its chemical compositions include triterpenoids, sterols, organic acids, and so on. The main antitumor active compositions of C21 steroids have been studied more than others. Modern pharmacological studies have shown the strong biological activity and the significant role on the antitumor, blood pressure, asthma and so on. Nowadays M. tenacissima and its preparation have extensive application in clinic. In this paper, pharmacological effects and clinical applications of M. tenacissima and its preparations had been reviewed to provide the theoretical basis for its further research.