| 凝血酶对体外培养的视网膜色素上皮细胞生长的影响 |
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| 引用本文： | 郑燕林,王万杰,袁晓辉,李晟,黄映红,曾洁萍. 凝血酶对体外培养的视网膜色素上皮细胞生长的影响[J]. 眼科研究, 2002, 20(6): 489-490 |
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| 作者姓名： | 郑燕林 王万杰 袁晓辉 李晟 黄映红 曾洁萍 |
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| 作者单位： | 610072,成都中医药大学临床医学院眼科 |
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| 基金项目： | 四川省教委重点科研基金资助(56) |
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| 摘 要： | 目的 探讨凝血酶对视网膜色素上皮细胞的影响。方法 利用体外培养的视网膜色素上皮细胞，观察不同浓度的凝血酶对视网膜色素上皮细胞的影响。结果 各浓度的凝血酶对体外培养的视网膜色素上皮细胞具有促进增殖的作用。且40U/ml尤为明显。结论 凝血酶对体外培养的视网膜色素上皮细胞具有促进增殖的作用。这为探讨增生性玻璃体视网膜病变的提供了实验依据。
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| 关 键 词： | 凝血酶 视网膜色素上皮细胞 增殖 体外培养 增生性玻璃体视网膜病变 |
| 修稿时间： | 2001-10-15 |
The effect of thrombin on cultured retinal pigment epithelial cells |
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| Zheng Yanlin,Wang Wanjie,Yuan Xiaohui,et al.. The effect of thrombin on cultured retinal pigment epithelial cells[J]. Chinese Ophthalmic Research, 2002, 20(6): 489-490 |
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| Authors: | Zheng Yanlin Wang Wanjie Yuan Xiaohui et al. |
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| Affiliation: | Zheng Yanlin,Wang Wanjie,Yuan Xiaohui,et al. Department of Ophthalmology,Affiliated Hospital of Chengdu Traditional Chinese Medicine University,Chengdu 610072 |
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| Abstract: | Objective To illustrate the effect of thromhin on growth of cultured retinal pigment epithelial. Method Cultured retinal pigment epithelial cells were exposed to different concentrations of thrombin in vitro and the proliferation of RPE was measured. Result Thrombin of different concentrations, especially that of 40 U/ml, promoted the proliferation of cultured retinal pigment epithelial. Conclusion Thrombin stimulted the proliferation of cultured retinal pigment epithelial. This finding provides an experimental basis for understanding mechanism of proliferative vitreoretinopathy. |
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| Keywords: | thrombin retinal pigment epithelial prolife |
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