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| 578.2 nm激光对不同黑色素含量兔视网膜损伤的比较 | |
| 引用本文： | 施东雯,顾瑛,张燕,张继庄,曾晶,蔡宏.578.2 nm激光对不同黑色素含量兔视网膜损伤的比较[J].中国激光医学杂志,2010,19(4):210-214,270. |
| 作者姓名： | 施东雯 顾瑛 张燕 张继庄 曾晶 蔡宏 |
| 作者单位： | 1. 空军总医院皮肤科,北京市,10036 2. 解放军总医院激光医学科 3. 天津市塘沽区中医院内科 4. 清华大学热力工程系 5. 解放军第316医院 |
| 基金项目： | 国家自然科学基金(30600493)北京自然科学基金 |
| 摘 要： | 目的比较脉宽20～40 ns、频率6 kHz的578.2 nm脉冲铜蒸气激光照射后不同黑色素含量兔视网膜的损伤阈值。方法以青紫蓝灰兔(16只,32只眼),新西兰大耳白兔(13只,26只眼)为实验对象,应用波长578.2mm,脉宽20～40ns的脉冲铜蒸气激光照射兔眼底视乳头下方的后极部,按照眼底功率密度将两组实验对象各分为五组,灰兔435 mW/cm~2、869 mW/cm~2、1 304 mW/cm~2、1948 mW/cm~2、2 898 mW/cm~2组和白兔869 mW/cm~2、1304 mW/cm~2、1593 mW/cm~2、2 174 mW/cm~2、3 043 mW/cm~2组。照光时间100 s,眼底光斑直径2 mm。照光后24 h检眼镜检查视网膜上的曝光点,眼底照相机检查和记录,组织病理学检查兔视网膜的损伤。结果波长578.2 nm,频率为6 kHz的铜蒸气激光,在眼底光斑直径为2 mm,照光时间为100 s的照光条件下,相同功率密度下灰兔视网膜损伤重于白兔。结论在照光时间相同和光斑大小不变的条件下,眼底色素含量是影响激光生物学效应的重要因素。 |
| 关 键 词： | 激光 视网膜 损伤阈值 |
Retinal Injury of Gray and White Rabbits by 578.2 nm Copper Vapor Laser: a Comparison |
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| SHI Dong-wen,GU Ying,ZHANG Yan,ZHANG Ji-zhuang,ZENG Jing,CAI Hong.Retinal Injury of Gray and White Rabbits by 578.2 nm Copper Vapor Laser: a Comparison[J].Chinese Journal of Laser Medicine & Surgery,2010,19(4):210-214,270. | |
| Authors: | SHI Dong-wen GU Ying ZHANG Yan ZHANG Ji-zhuang ZENG Jing CAI Hong |
| Institution: | SHI Dong-wen~1,GU Ying~(2*),ZHANG Yan~3,ZHANG Ji-zhuang~4,ZENG Jing~2,CAI Hong~5 1.Department of Dermatology,General Hospital of Air Force,Beijing 100036,China 2.Department of Laser Medicine,Chinese PLA General Hospital 3.Department of Internal Medicine,Traditional Chinese Medicine Hospital of Tanggu 4.Thermal Engineering Department,Tsinghua University 5.PLA No.316 Hospital |
| Abstract: | Objective Using the 578.2 nm laser pulses with pulsewidths of 20-40 ns on the retinas of rabbit eyes with different pigment quantity, to compare the retinal injury thresholds in different rabbit eyes. Methods Thirty-two eyes of 16 gray rabbits and 26 eyes of 13 white rabbits were exposed to the laser with wavelengths of 578.2 nm, with the duration of 100 s and the spot size of 2 mm.The gray rabbits were grouped by density as 435 mW/cm~2,869 mW/cm~2,1 304 mW/cm~2,1 948 mW/cm~2 and 2 898 mW/cm~2.The white rab... |
| Keywords: | Laser Retina Injury thresholds |
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