356例高血压住院患者素食与中医证候特征调查分析

目的]调查高血压患者中医证候类型和饮食情况,分析素食与高血压中医证候之间的相关性。方法]采用流行病学研究方法,选择山东中医药大学附属医院2015年7月1日—12月31日收治的356例高血压住院患者,应用食物频率法调查饮食情况,依据《中药新药临床研究指导原则》辨别高血压中医证型,多因素logistic回归分析素食与高血压中医证型的关系。结果]素食组(蔬菜水果占饮食结构的80%及以上者)187例,其中低强度组(蔬菜水果占饮食结构的80%-90%者)120例,高强度组(蔬菜水果占饮食结构的90%及以上者)67例;痰湿壅盛型142例(39.89%),肝火亢盛型101例(28.37%),阴阳两虚型80例(22.47%);素食强度是痰湿壅盛型、肝火亢盛型、阴虚阳亢型的相关因素(P0.05),其OR值分别为13.259、0.237、0.591。结论]素食与高血压痰湿壅盛型、肝火亢盛型和阴虚阳亢型有相关性,适当增加素食比例能降低痰湿壅盛型高血压的发生。

Analysis between vegetarian and syndrome characteristics of traditional Chinese medicine for 356 cases hospitalized patients with hypertension

Objective] To investigate the syndrome type of traditional Chinese medicine and diets of hospitalized patients with hypertension, and to analysis the correlation between vegetarian diets and syndrome type of hypertension of traditional Chinese medicine. Methods] Adopt the method of epidemiological investigation, 356 cases of hospitalized patients with hypertension from July 1, 2015 to December 31, 2015 in affiliated hospital of Shandong University of traditional Chinese medicine were selected. The diet of patients was investigated by the method of food frequency. The hypertension syndrome type of traditional Chinese medicine was determined by referring to The New Chinese Medicine Clinical Guideline. Multi-factor logistic regression analysis was used to analyze the relationship between vegetarian with hypertension traditional Chinese medicine syndrome type. Results] Vegetarian group (the proportion of fruits and vegetables is more than 80% among the diet) had 187 cases, low-intensity group (the proportion of fruits and vegetables is between 80% and 90% among the diet) had 120 cases and high-intensity group (the proportion of fruits and vegetables is more than 90% among the diet) had 67 cases. Phlegmatic hygrosis type had 142 cases (39.89%), liver fire exuberance type had 101 cases(28.37%), yin yang concurrent deficiency type had 80 cases(22.47%).The vegetarian ratio was a relevant factor for Phlegmatic hygrosis type, liver fire exuberance type and yin deficiency yang hyperactivities type. The OR values were 13.259, 0.237 and 0.591 respectively. Conclusion] There is correlation between the vegetarian ratio among Phlegmatic hygrosis type, liver fire exuberance type and yin deficiency yang hyperactivities type. Increasing the vegetarian ratio properly can decline the risk of Phlegmatic hygrosis type of hypertension.