Clinical Study on Kangquan Recipe (康泉方) for Benign Prostatic Hyperplasia Patients: A Randomized Controlled Trial |
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作者姓名: | HUANG Yuan-peng WEN Yan-hui WU Geng-hui HONG Zhen-feng |
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作者单位: | Department of Traditional Chinese Medicine,Zhongshan Hospital,Xiamen University;Academy of Integrative Medicine,Fujian University of Traditional Chinese Medicine |
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基金项目: | Supported by the Foundation of Science and Technology Department of Xiamen(No.3502Z20084014);the Foundation ofKey Projects from Science and Technology Department of Fujian Province(No.2012D064);the Foundation of Traditional Chinese Medicine of Fujian Province(No.wst201208) |
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摘 要: | Objective:To observe the effectiveness and safety of Kangquan Recipe(康泉方,KQR) for benign prostatic hyperplasia(BPH) patients.Methods:One hundred and six BPH patients were randomly assigned to the treatment group(53 cases) and the control group(53 cases) according to a random number table.The treatment group was given KQR orally;the control group was given cemilton orally.After 24-week treatment,the clinical effect and safety were evaluated using the International Prostatic Symptom Score(l-PSS),quality of life(QOL),maximum flow rate(Qmax),average flow rate(Qave),residual urine volume(RUV),total prostatic volume(TPV),etc.Results:After treatment,the score of l-PSS was decreased from 16.9 ±5.6 to 12.5 ±4.6in the treatment group,significantly lower compared with the control group;the levels of Qmax and Qave were from 10.9 ±3.5 to 15.6 ±4.5 and 5.4 ±2.1 to 7.3 ±2.5(mL/s) in the treatment group,significantly higher compared with the control group;the levels of RUV and TPV were from 70.8 ±28.2 to 35.2 ±21.8 and37.2 ± 16.9 to 30.1 ± 10.8(mL) in the treatment group,significantly lower compared with the control group(all P〈0.05).The incidence rate of adverse reaction was similar between the two groups(P〉0.05).Conclusion:KQR is effective and safe for the treatment of BPH.
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关 键 词: | 良性前列腺增生 随机对照试验 临床效果 患者 水平距离 对照组 随机分配 安全使用 |
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